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International Symposium: Changing the tumor microenvironment: New strategies for immunotherapy

Life and Material Sciences | Pamplona, March 21-22, 2012

Program

Coordinators:
Ignacio Melero
Centro de Investigación Médica Aplicada (CIMA). Clínica Universidad de Navarra. Universidad de Navarra. Pamplona. Spain.
Pedro Berraondo
Centro de Investigación Médica Aplicada (CIMA). Clínica Universidad de Navarra. Universidad de Navarra. Pamplona. Spain.
Viktor Umansky
Cancer Research Center (DKFZ). Heidelberg. Mannheim University Hospital. Mannheim. Germany.

Wednesday, 21

08:30 Presentation
Raimundo Pérez-Hernández y Torra
Director. Fundación Ramón Areces. Spain.
Ignacio Melero
Symposium Coordinator.

Chairman:
Juan José Lasarte
Centro de Investigación Médica Aplicada (CIMA). Pamplona. Spain.

09:0o The immune microenvironment of human tumors
Wolf Hervé Fridman
Cordeliers Research Centre. Paris. France.

9:40 Myeloid-derived suppressor cells in tumor microenvironment. Possible target for therapeutic intervention
Dmitry Gabrilovich 
H. Lee Moffitt Cancer Center and Research Institute. University of South Florida. Tampa. United States.

10:20 Hypoxia, CD137, tumor infiltrating lymphocytes and endothelium

11:00 Break
Chairman:
Juan Ruiz 
Digna Biotech. Madrid. Spain.

11:20 Overcoming immunosuppression induced by chronic inflammation in melanoma microenvironment
Viktor Umansky 
Symposium Coordinator.

12:00 Development of immunotherapy strategies aimed at blocking the immunosuppressor tumor microenvironment and enhancing antitumor immune responses
Pedro Berraondo 
Symposium Coordinator.

12:40 Immunity and inflammation in the microenvironment of primary melanomas: using the Hgf-Cdk4 mouse model
Thomas Tuting 
Department of Dermatology. University of Bonn. Germany.

13:20 Role of cancer metabolism in adaptive and innate immunity
Licia Rivoltini 
Unit of Immunotherapy of Human Tumors. National Institute of Tumors. Milano. Italy.

14:00 Break
Chairwoman:
Sandra Hervás-Stubbs 
Centro de Investigación Médica Aplicada (CIMA). Pamplona. Spain.

16:00 Chemokines and the microenvironment in human melanoma
Paloma Sánchez Mateos 
Hospital General Universitario Gregorio Marañón. Madrid. Spain.

16:40 Integrin dependent dendritic cell interaction with lymphatic endothelium under inflammatory conditions
Ana Rouzaut  
Centro de Investigación Médica Aplicada (CIMA). Pamplona. Spain.

17:20 CCR5 in cancer immunotherapy: More than an "attractive" receptor for T cells
Santos Mañes 
Centro Nacional de Biotecnología. Madrid. Spain.

18:00 Role of MHC class I altered expression in cancer progression and resistance to immunotherapy
Teresa Cabrera 
Universidad de Granada. Spain.

Thursday, 22

Chairwoman:
Ana Rouzaut

08:30 Cooperation between interleukin-12 and oxaliplatin for the establishment of an efficient immune response against colon cancer
Rubén Hernández  
Centro de Investigación Médica Aplicada (CIMA). Pamplona. Spain.

09:10 Conditioning tumor environment to facilitate CD8+ T cell entry and function
Pawel Kalinski   
University of Pittsburgh and the University of Pittsburgh Cancer Institute. Pittsburgh. United States. 

09:50 Studying T cell-endothelial interactions to improve the immunotherapy toolbox
George Coukos  
Ovarian Cancer Research Center. University of Pennsylvania. Philadelphia. United States.

10:30 Cancer macroenvironment and immmune evasion
Vincenzo Bronte  
Venetian Institute of Molecular Medicine. Padova. Italy.

11:10 Break
Chairman:
Viktor Umansky 

11:30 Building on the success of CTLA-4 blockade using combination strategies and other immune modulators
Jedd Wolchok  
Memorial Sloan-Kettering Cancer Center. New York. United States.

12:10 Targeting regulatory dendritic cells in the tumor microenvironment
Michael Shurin 
Department of Pathology. University of Pittsburgh Medical Center. Pittsburgh. United States.

12:50 Gene profiling of the tumor microenvironment
Ena Wang 
National Institutes of Health. Bethesda. United States.

13:30 Final remarks and meeting adjourn

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