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Projects. Life and Matter Sciences

The genome and epigenome

16th National Programme

June 27, 2012 - June 27, 2015

Study of the methylome/genome relationship and their points in common in systemic autoimmune diseases: SLE, RA and SSc
Lead Researcher: Esteban Ballestar Tarín
Research Centre: Instituto de Investigación Biomédica de Bellvitge (IDIBELL). Barcelona. (Spain).

Nutri-epigenetics of the control of body adiposity: studies in animal models of differing susceptibility to obesity based on nutritional interventions in early stages in life
Lead Researcher: María Luisa Bonet Piña
Research Centre: Universidad de las Islas Baleares. Mallorca. (Spain).

Epigenome and transcriptome of nociception (Functional epigenomics of nociception)
Lead Researcher: Ángel Manuel Carrión Rodríguez
Research Centre: Facultad de Ciencias Experimentales. Universidad Pablo de Olavide. Sevilla. (Spain).

The acetylomes of neural differentiation
Lead Researcher:
Mario Fernández Fraga
Research Centre: Instituto Universitario de Oncología del Principado de Asturias (IUOPA)-Universidad de Oviedo. (Spain).

Epigenetic alterations in tetraploid neurones and Alzheimer's disease
Lead Researcher: José María Frade López
Research Centre: Instituto Cajal. CSIC. Madrid. (Spain).

Experimental study of the epigenetic implications of changes in the composition of fatty acids in the diet during pregnancy and their consequences for adult offspring
Lead Researcher:
Emilio Herrera Castillón
Research Centre: Universidad San Pablo-CEU. Madrid. (Spain).

The epigenetic regulation of reelin in Alzheimer's disease
Lead Researcher: Javier Sáez Valero
Research Centre: Instituto de Neurociencias. CSIC-Universidad Miguel Hernández. Alicante. (Spain).

15th National Programme

16th March 2010 - 16th March 2013

Transcription factors and heterochromatin formation in Drosophila 
Lead Researcher: Natalia Azpiazu Torres
Research Centre: Centro de Biología Molecular "Severo Ochoa". CSIC-UAM. (Spain).

Role of epigenetic mechanisms in the processes of learning and memory

Lead Researcher: Ángel Manuel Carrión Rodríguez
Research Centre: Facultad de Ciencias Experimentales. Universidad Pablo de Olavide. Sevilla. (Spain).

Association between non-coding RNAs in ultra-conserved regions (T-UCR) and the epigenome: involvement in cancer
Lead Researcher: Manel Esteller Badosa
Research Centre: Programa de Epigenética y Biología del Cáncer. Institut d'Investigació Biomédica de Bellvitge (IDIBELL). Barcelona. (Spain).

High resolution profiles of acetylation and methylation of histones in the epigenome of Arabidopsis thaliana: functional connection with the biological clock
Lead Researcher: Paloma Más Martínez
Research Centre: Consorcio CSIC-IRTA-UAB. Centro de Investigación en Agrigenómica (GRAG). Barcelona. (Spain).

Search and identification of new genetic and epigenetic causes of autistic spectrum disorders: design and implementation of a targeted high-resolution array with key elements of the epigenetic machinery
Lead Researcher: María del Carmen Orellana Alonso
Research Centre: Hospital Universitario La Fe. Valencia. (Spain).

Epigenetic control of cell differentiation and pluripotency by BRAF35 AND iBRAF proteins
Lead Researcher: José Carlos Reyes Rosa
Research Centre: Centro Andaluz de Biología Molecular y Medicina Regenerativa. CSIC. Sevilla. (Spain). 

Epigenetic regulation of the maintenance of genomic stability during mitotic and meiotic cell cycle
Lead Researcher: Pedro Antonio San Segundo Nieto
Research Centre: Instituto de Microbiología Bioquímica. CSIC-Universidad de Salamanca. (Spain).

Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system
Lead Researcher: Miguel Ángel Vidal Caballero
Research Centre: Centro de Investigaciones Biológicas. CSIC. Madrid. (Spain).

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