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Projects. Life and Earth Sciences

Development of Lab-on-a-chip nanostructured sensors for the detection of pathogens and food-borne chemical agents based on Surface-Enhanced Raman Spectroscopy (SERS)

Lead Researcher: Jorge Pérez Juste
Research Centre: Facultad de Química. Universidad de Vigo.

Abstract: 

Jorge Pérez JusteThe main objective of the project SERSforSAFETY is to design and develop miniaturized "lab-on-a-chip" diagnostic platforms based on surface-enhanced Raman spectroscopy for the subsequent fabrication of sensitive point of care devices, fast and portable that allow the ultra-detection of bacteria and various chemical contaminants. In order to achieve our objectives, we will apply synthetic methodologies developed in the Nanochemistry and Materials Science fields since the diagnostic platforms will be based on assemblies of plasmonic metal nanoparticles (Au mainly) deposited on porous filtering membranes (such as paper) or on glass substrates designed by soft photolithography techniques. Once the materials have been manufactured, the next objective is to demonstrate their applicability in the field of sensors, and particularly towards the biodetection of different analytes in complex media such as food. To this end, their ability to detect different pathogenic microorganisms and chemical contaminants by SERS will be evaluated. Finally, we will address the main objective of the project: the development of a miniaturized "lab-on-a-chip" diagnostic platform and its application in Point-of-Care devices for ultra-detection of pathogenic microorganisms and chemical contaminants in real samples.


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