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Genetics & ALS: Implications and challenges in knowledge, diagnosis and disease management

Life and Matter Sciences

Fra Papers 2019


Alberto García Redondo
John Landers
Adolfo López de Munain
Ana Cristina Calvo
Caterina Bendotti
Maria Antonia Barceló
Pedro Vizán
Ammar Al-Chalabi
Valentina Gallo
Ernest Milián
Mimoun Azzou
Rosario Osta

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As with other major neurodegenerative diseases such as Alzheimer’s or Parkinson’s disease ,Amyotrophic Lateral Sclerosis (ALS) is a disease that can be hereditary. It is known that 5 to 10% of patients with ALS have or have had fi rst or second-degree family members with the same disease or frontotemporal dementia. It has focused on the genetic implications and the challenges in knowledge, diagnosis and management of the disease.

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