Research projects
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Application of biomaterials with angiogenic, antioxidant and regenerative purposes in the central nervous system
15th National Programme for the allocation of Research Grants for Life and Matter Sciences
Biomimetic models
Research Centre or Institution : Faculty of Health Sciences. CEU-Cardenal Herrera University. Valencia. (Spain)
Abstract
Currently, the vast majority of neurodegenerative disorders that affect brain structures lack an effective clinical strategy for their treatment. Regenerative medicine aims in these cases to achieve an approach based on cell transplantation. However, it needs to have a cell support structure that allows positioning and functional behaviour. It is therefore of the utmost importance to identify synthetic, biodegradable and stable materials, compatible with brain tissue, and capable of promoting angiogenesis processes which ensure the formation of blood vessels inside for adequate cell survival inside the scaffolding. The project goals are the identification of materials on which neural cells are viable and functional. For the development of this study, in vitro studies will be developed to determine the viability, proliferation and differentiation of vascular endothelial cells. In parallel, the viability the use of biomaterials will be studied in vivo along with the characterisation of their functional integration in an experimental mouse model with local brain damage.
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30
Jan
2023
Panel Discussion Biomateriales: Impacto Social Madrid, Monday, 30 January 2023, 17:00 hours
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16
Feb
2023
Ciclo de conferencias y debates en ciencias Cellular therapies: New oportunities offered by genetic engineering and immunotherapy Madrid, Thursday, 16 February 2023, 17:30 hours
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7
Mar
2023
International Symposium Membrane-Less Organelles in Cell Life and Disease Sevilla, Tuesday and Wednesday, 7 and 8 March 2023, 10:15 hours
- Study of EBV, HHV-6A AND HHV-6B MICRO-RNAs in plasma isolated exosomes of patients with multiple sclerosis: correlation with activity and progression of disease 2016 Senior Researcher : Roberto Álvarez Lafuente Research Centre or Institution : Hospital Universitario Clínico San Carlos. Instituto de Investigación Sanitaria San Carlos (IdISSC). Madrid.
- Modulation of exosomes transporting miRNAs and lncRNAs for intercellular communication as therapeutic tools in dyslipidemia treatment 2016 Senior Researcher : Alberto Dávalos Herrera
- Regioselective manipulation of carbon spheres to revolutionize the efficiency of solar cells (RegioSolar) 2020 Senior Researcher : Xavier Ribas Salamaña Research Centre or Institution : Parc Científic i Tecnològic de la Universitat de Girona
Stem cells and organoids. Unlocking their potential to understand and treat disease
Febrero 2018 Nature Papers
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