Research projects
Start of main content
Development of Lab-on-a-chip nanostructured sensors for the detection of pathogens and food-borne chemical agents based on Surface-Enhanced Raman Spectroscopy (SERS)
18th national competition for scientific and technical research
Food security and biotechnology
Senior Researcher : Jorge Pérez Juste
Abstract
The main objective of the SERSforSAFETY project is to design and develop miniaturized "lab-on-chip" diagnostic platforms based on Surface enhanced Raman spectroscopy for the subsequent manufacture of sensitive, fast and portable point-of-care devices for the ultrasensitive detection of bacteria and various chemical contaminants. To achieve our objectives, we will apply synthetic methodologies developed in the fields of Nanochemistry and Materials Science to fabricate sensing platforms based on plasmonic metal nanoparticles deposited in porous filter membranes (such as paper) or glass substrates designed by soft photolithography techniques. Once the materials are manufactured, the next objective is to demonstrate their applicability in the field of sensors, and in particular towards the bio-detection of different analytes in complex media such as food.
To this end, its ability to detect different pathogenic microorganisms and chemical contaminants by SERS spectroscopy will be evaluated. Finally, we will address the main objective of the project: the development of a miniaturized diagnostic platform "lab on chip" and its application in point-of-care devices for the ultra-detection of pathogenic microorganisms and chemical contaminants in real samples. At the current stage, we are developing a lab on a chip system based on a lateral flow immunoassay for simultaneous detection of different allergens and contaminants. To this end, different metal nanoparticles encoded with active molecules in Raman have been synthesized, which will be bioconjugated with antibodies specific to allergens and contaminants to be detected.
Scientific Production |
|
---|---|
Magazine Articles | 7 |
Communications at national conferences | 6 |
Communications at international conferences | 17 |
- Activities related
- Projects related
- News related
- Publications related
-
11
Jan
2022
Conversaciones online desde la Fundación Ramón Areces Del control del desarrollo vegetal a la biotecnología: fortalezas y debilidades ONLINE www.fundacionareces.tv/directo, Tuesday, 11 January 2022, 19:00 hours
-
7
Jun
2022
Conference Materiales de nanoingeniería: retos y oportunidades Madrid, Tuesday, 7 June 2022, 19:00 hours
-
29
Nov
2022
Conferencia online Combustibles innovadores para un transporte aéreo sostenible ONLINE www.fundacionareces.tv/directo, Tuesday, 29 November 2022, 19:00 hours
- New food-derived bioactive products against obesity and diabetes 2016 Senior Researcher : Pablo José Fernández Marcos Research Centre or Institution : Instituto Madrileño de Estudios Avanzados (IMDEA) en Alimentación. Madrid.
- Understanding the connection between ROS/RNS homeostasis and the circadian signalling network: beyond the genetic level 2020 Senior Researcher : María del Carmen Martí Ruiz Research Centre or Institution : Centro de Edafología y Biología Aplicada del Segura (CEBAS-CSIC)
- Nutritional formulae for docosahexaenoic acid (DHA) and arachidonic (AA) deficiency control in extreme premature infants 2020 Senior Researcher : Miguel Sáenz de Pipaón Marcos Research Centre or Institution : Fundación para la Investigación Biomédica. Hospital Universitario La Paz. Madrid.
End of main content