Jump Main Menu. Go directly to the main content

Sección de idiomas


Fin de la sección de idiomas

Access / Registration

Sección de utilidades

Fin de la sección de utilidades

Secondary menu End of secondary menu

Research projects

Start of main content

Investigation on hybrid molecules as powerful novel therapeutic approaches for Multiple Sclerosis and myelin- related rare diseases

19th national competition for scientific and technical research

Amyotrophic Lateral Sclerosis (ALS) and Multiple Sclerosis (MS): Molecular Etiology and Novel Treatments

Senior Researcher : Fernando de Castro Soubriet

Research Centre or Institution : Instituto Cajal. CSIC. Madrid.


Together with the group of Dr. Valle Palomo at IMDEA Nanociencia, we have continued our work in the following work pipeline:

A second extended in vivo study of protection in the experimental autoimmune encephalomyelitis model of an LRRK-2 inhibitor molecule has been performed. Objective: To determine whether an LRRK2 inhibitor molecule capable of inducing the proliferation and differentiation of oligodendrocyte precursor cells could recover the symptoms in an in vivo model of multiple sclerosis. Results: It has been observed that the tested molecule is capable of reducing the clinical symptoms in a statistically significant manner in this model and of reducing histological lesions and therefore is a proposed candidate for the treatment of this disease. Next Steps: An article on the results is currently being written for publication with the following title and participating authors:


Scientific Production
Magazine Articles 1
Communications at national conferences -
Communications at international conferences 2


  • Activities related
  • Projects related
  • News related
  • Publications related

see all

End of main content