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The biomimetic sealing of dental implants (BIOSELLADO)

16th national competition for scientific and technical research

Biomimetic models

Senior Researcher : Daniel Rodríguez Rius

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Research Centre or Institution : Universidad Politécnica de Cataluña. Barcelona.


The objective of this project is to modify the surface of titanium according to biomimetic models, to reduce failures due to bacterial infections in dental implants (peri-implantitis). To this end, the aim is to achieve the biological sealing of the implant with oral tissue by means of anchoring sequences of adhesion for the cells of the gum tissue over a coating that is antiadhesive for bacteria, in combination with the biomimetic deposition of apatite on the surfaces in contact with the bone tissue, to improve osteointegration.

The effect of these modifications will be studied in vitro to evaluate the reduction in bacterial adhesion and growth on the treated surface, as well as to evaluate any possible effects on gingival cells and osteoblasts. Once the best treatments have been selected, they will be used on a type of implant in the respective areas of contact with the bone tissue and gingival tissue, and will be tested in vivo in an animal model.

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