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18th national competition for scientific and technical research

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Cell therapy in neurodegenerative diseases

Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. Rescue of the phenotype and cell transplantation
Cell therapy in neurodegenerative diseases Call: 2016
Senior Researcher : Carlos Vicario Abejón Research Centre or Institution : Instituto Cajal. CSIC. Madrid. Call: 18th national competition for scientific and technical research
more information on Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. Rescue of the phenotype and cell transplantation

Exosomes: intercellular communication as a therapeutic weapon

Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
Exosomes: intercellular communication as a therapeutic weapon Call: 2016
Senior Researcher : Fernando Rodríguez Serrano Call: 18th national competition for scientific and technical research
more information on Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
Characterization of infection biomarkers and possible drug targets present into exosome vesicles generated during in vitro and in vivo infection by Leishmania infantum
Exosomes: intercellular communication as a therapeutic weapon Call: 2016
Senior Researcher : Vicente Emilio Larraga Rodríguez de Vera Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC) Call: 18th national competition for scientific and technical research
more information on Characterization of infection biomarkers and possible drug targets present into exosome vesicles generated during in vitro and in vivo infection by Leishmania infantum
Investigating the molecular mechanisms of exosome production under cellular stress
Exosomes: intercellular communication as a therapeutic weapon Call: 2016
Senior Researcher : Antonio Zorzano Olarte Research Centre or Institution : Instituto de Investigación Biomédica (IRB) Barcelona. Call: 18th national competition for scientific and technical research
more information on Investigating the molecular mechanisms of exosome production under cellular stress
Modulation of exosomes transporting miRNAs and lncRNAs for intercellular communication as therapeutic tools in dyslipidemia treatment
Exosomes: intercellular communication as a therapeutic weapon Call: 2016
Senior Researcher : Alberto Dávalos Herrera Call: 18th national competition for scientific and technical research
more information on Modulation of exosomes transporting miRNAs and lncRNAs for intercellular communication as therapeutic tools in dyslipidemia treatment
Study of EBV, HHV-6A AND HHV-6B MICRO-RNAs in plasma isolated exosomes of patients with multiple sclerosis: correlation with activity and progression of disease
Exosomes: intercellular communication as a therapeutic weapon Call: 2016
Senior Researcher : Roberto Álvarez Lafuente Research Centre or Institution : Hospital Universitario Clínico San Carlos. Instituto de Investigación Sanitaria San Carlos (IdISSC). Madrid. Call: 18th national competition for scientific and technical research
more information on Study of EBV, HHV-6A AND HHV-6B MICRO-RNAs in plasma isolated exosomes of patients with multiple sclerosis: correlation with activity and progression of disease

Food security and biotechnology

Advanced photo systems with biocidal properties for coatings development with application in food and hospital safety
Food security and biotechnology Call: 2016
Senior Researcher : Ana Iglesias Juez Research Centre or Institution : Instituto de Catálisis y Petroleoquímica. CSIC. Madrid. Call: 18th national competition for scientific and technical research
more information on Advanced photo systems with biocidal properties for coatings development with application in food and hospital safety
Development of Lab-on-a-chip nanostructured sensors for the detection of pathogens and food-borne chemical agents based on Surface-Enhanced Raman Spectroscopy (SERS)
Food security and biotechnology Call: 2016
Senior Researcher : Jorge Pérez Juste Call: 18th national competition for scientific and technical research
more information on Development of Lab-on-a-chip nanostructured sensors for the detection of pathogens and food-borne chemical agents based on Surface-Enhanced Raman Spectroscopy (SERS)
New food-derived bioactive products against obesity and diabetes
Food security and biotechnology Call: 2016
Senior Researcher : Pablo José Fernández Marcos Research Centre or Institution : Instituto Madrileño de Estudios Avanzados (IMDEA) en Alimentación. Madrid. Call: 18th national competition for scientific and technical research
more information on New food-derived bioactive products against obesity and diabetes
Novel insights, tools and measures to mitigate emerging risk by yeasts in the food chain
Food security and biotechnology Call: 2016
Senior Researcher : Amparo Querol Simón Research Centre or Institution : Instituto de Agroquímica y Tecnología de Alimentos. CSIC. Paterna, Valencia. Call: 18th national competition for scientific and technical research
more information on Novel insights, tools and measures to mitigate emerging risk by yeasts in the food chain
Towards a new paradigm in the identification of hazards and evaluation of the safety and risk of neurotoxicity associated to the exposure to nanomaterials with biotechnological applications
Food security and biotechnology Call: 2016
Senior Researcher : Miguel Ángel Sogorb Sánchez Research Centre or Institution : Instituto de Bioingeniería. Universidad Miguel Hernández de Elche. Call: 18th national competition for scientific and technical research
more information on Towards a new paradigm in the identification of hazards and evaluation of the safety and risk of neurotoxicity associated to the exposure to nanomaterials with biotechnological applications
Using animal models for testing interventions targeting malnutrition and stunting in children
Food security and biotechnology Call: 2016
Senior Researcher : Fernando Martín Belmonte Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Using animal models for testing interventions targeting malnutrition and stunting in children

Graphene, foundations and applications

Controlling the magnetism and electronic transport of graphene samples at the atomic scale
Graphene, foundations and applications Call: 2016
Senior Researcher : Iván Brihuega Álvarez Research Centre or Institution : Universidad Autónoma de Madrid. Call: 18th national competition for scientific and technical research
more information on Controlling the magnetism and electronic transport of graphene samples at the atomic scale
Graphene-based flexible neural interfaces for the peripheral nervous system
Graphene, foundations and applications Call: 2016
Senior Researcher : José Antonio Garrido Ariza Research Centre or Institution : Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona. Call: 18th national competition for scientific and technical research
more information on Graphene-based flexible neural interfaces for the peripheral nervous system
Graphene: macrophage biomaterials: functional characterization for the use in cardiovascular pathologies
Graphene, foundations and applications Call: 2016
Senior Researcher : Lisardo Boscá Gomar Research Centre or Institution : Instituto de Investigaciones Biomédicas "Alberto Sols". CSIC-Universidad Autónoma de Madrid. Call: 18th national competition for scientific and technical research
more information on Graphene: macrophage biomaterials: functional characterization for the use in cardiovascular pathologies

Immunotherapy and cancer

Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
Immunotherapy and cancer Call: 2016
Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
Immunotherapy and cancer Call: 2016
Senior Researcher : Eva Martín del Valle Research Centre or Institution : Universidad de Salamanca Call: 18th national competition for scientific and technical research
more information on Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
Development of new targets for immunotherapy in cancer metastasis
Immunotherapy and cancer Call: 2016
Senior Researcher : José Ignacio Casal Álvarez Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC) Call: 18th national competition for scientific and technical research
more information on Development of new targets for immunotherapy in cancer metastasis
From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
Immunotherapy and cancer Call: 2016
Senior Researcher : Enrique María Ocio San Miguel Call: 18th national competition for scientific and technical research
more information on From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
Immunotherapy and cancer Call: 2016
Senior Researcher : Juan José Lasarte Sagastibelza Call: 18th national competition for scientific and technical research
more information on Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
Immunotherapy and cancer Call: 2016
Senior Researcher : Ángel Carracedo Álvarez Research Centre or Institution : Fundación Pública Gallega de Medicina Genómica. Santiago de Compostela. Call: 18th national competition for scientific and technical research
more information on Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
Immunotherapy and cancer Call: 2016
Senior Researcher : Carlos Martínez Alonso Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid Call: 18th national competition for scientific and technical research
more information on The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
Transforming EGFR expressing tumors into immune-rejectable tissues
Immunotherapy and cancer Call: 2016
Senior Researcher : Fernando Pastor Rodríguez Call: 18th national competition for scientific and technical research
more information on Transforming EGFR expressing tumors into immune-rejectable tissues

Interactome: pathological implications

Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators
Interactome: pathological implications Call: 2016
Senior Researcher : Yolanda Revilla Novella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators
Identification of the nucleotide cellular sensor and its interactome
Interactome: pathological implications Call: 2016
Senior Researcher : Marçal Pastor Anglada Research Centre or Institution : CIBEREHD - Universidad de Barcelona Call: 18th national competition for scientific and technical research
more information on Identification of the nucleotide cellular sensor and its interactome
Interactions of the protein N-acetylglucosamine kinase with different elements of gene regulation in Yarrowia lipolytica
Interactome: pathological implications Call: 2016
Senior Researcher : Carlos Gancedo Rodríguez Research Centre or Institution : Instituto de Investigaciones Biomédicas "Alberto Sols". CSIC-Universidad Autónoma de Madrid. Call: 18th national competition for scientific and technical research
more information on Interactions of the protein N-acetylglucosamine kinase with different elements of gene regulation in Yarrowia lipolytica
Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons
Interactome: pathological implications Call: 2016
Senior Researcher : María Jesús Bullido Gómez-Heras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons
WIP differential interactome during its oncogenic or tumor suppressor activity
Interactome: pathological implications Call: 2016
Senior Researcher : Inés María Antón Gutiérrez Research Centre or Institution : CIBERNED/CNB-CSIC. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas-Centro Nacional de Biotecnología. Madrid Call: 18th national competition for scientific and technical research
more information on WIP differential interactome during its oncogenic or tumor suppressor activity

Rare diseases

A knowledge-based pipeline to increase the diagnosis rate of Rare Diseases using deep sequencing
Rare diseases Call: 2016
Senior Researcher : Carmen Ayuso García Research Centre or Institution : Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM). CIBERER. Madrid. Call: 18th national competition for scientific and technical research
more information on A knowledge-based pipeline to increase the diagnosis rate of Rare Diseases using deep sequencing
Activation of innate immunity in dysferlin-deficient cells: new therapeutic targets
Rare diseases Call: 2016
Senior Researcher : Noemí de Luna Salvà Call: 18th national competition for scientific and technical research
more information on Activation of innate immunity in dysferlin-deficient cells: new therapeutic targets
AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies
Rare diseases Call: 2016
Senior Researcher : Jorgina Satrústegui Gil-Delgado Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies
Astrocytes: new anti-epileptic targets in Lafora disease
Rare diseases Call: 2016
Senior Researcher : Pascual Felipe Sanz Bigorra Call: 18th national competition for scientific and technical research
more information on Astrocytes: new anti-epileptic targets in Lafora disease
Dyskeratosis congenita. New models, New molecular keys and New treatments
Rare diseases Call: 2016
Senior Researcher : María Luisa Cayuela Fuentes Research Centre or Institution : Hospital Clínico Universitario Virgen de la Arrixaca. Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca. El Palmar, Murcia. Call: 18th national competition for scientific and technical research
more information on Dyskeratosis congenita. New models, New molecular keys and New treatments
Modeling of familial cerebral cavernous malformation through cellular reprogramming
Rare diseases Call: 2016
Senior Researcher : Miguel Ángel Fidalgo Pérez Research Centre or Institution : Centro de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS). Universidad de Santiago de Compostela Call: 18th national competition for scientific and technical research
more information on Modeling of familial cerebral cavernous malformation through cellular reprogramming
Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
Rare diseases Call: 2016
Senior Researcher : César Cobaleda Hernández Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
Phosphodiesterase inhibitors as Friedreich's ataxia treatment
Rare diseases Call: 2016
Senior Researcher : Pilar González Cabo Research Centre or Institution : Centro de Investigación Biomédica en Red (CIBER de Enfermedades Raras). Facultad de Medicina y Odontología. Universidad de Valencia Call: 18th national competition for scientific and technical research
more information on Phosphodiesterase inhibitors as Friedreich's ataxia treatment
Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases
Rare diseases Call: 2016
Senior Researcher : Paola Bovolenta Nicolao Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases
The connection between rare diseases and common diseases: dysfunction of copper homeostasis and mitochondria as a model (NeuroCopper)
Rare diseases Call: 2016
Senior Researcher : Francesc Palau Martínez Research Centre or Institution : Instituto de Investigación Sanitaria Sant Joan de Déu y Hospital Sant Joan de Déu. Barcelona. Call: 18th national competition for scientific and technical research
more information on The connection between rare diseases and common diseases: dysfunction of copper homeostasis and mitochondria as a model (NeuroCopper)
The function of the E3 ubiquitin ligase APC/C-Cdh1 in Fragile X Syndrome. Possible therapeutic application
Rare diseases Call: 2016
Senior Researcher : Ángeles Almeida Parra Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca. Call: 18th national competition for scientific and technical research
more information on The function of the E3 ubiquitin ligase APC/C-Cdh1 in Fragile X Syndrome. Possible therapeutic application
Towards the improvement of diagnosis and treatment in Congenital Dyserythropoyetic Anaemias
Rare diseases Call: 2016
Senior Researcher : María del Carmen Sánchez Fernández Research Centre or Institution : Instituto de Investigación contra la Leucemia Josep Carreras (IJC). Barcelona. Call: 18th national competition for scientific and technical research
more information on Towards the improvement of diagnosis and treatment in Congenital Dyserythropoyetic Anaemias
Visualisation of neuronal polysomal architecture and its alterations in Huntington's Disease
Rare diseases Call: 2016
Senior Researcher : José Jesús Fernández Rodríguez Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid Call: 18th national competition for scientific and technical research
more information on Visualisation of neuronal polysomal architecture and its alterations in Huntington's Disease

Renewable energy: materials and processes

Development of Mimics of Hidrogenases Modulated by Transition Metal Complexes to Produce Hydrogen in the Absence of Molecular Reducing Agents
Renewable energy: materials and processes Call: 2016
Senior Researcher : Miguel A. Sierra Rodríguez Call: 18th national competition for scientific and technical research
more information on Development of Mimics of Hidrogenases Modulated by Transition Metal Complexes to Produce Hydrogen in the Absence of Molecular Reducing Agents
Efficient materials for the capture and selective transformation of CO2 towards value-added chemicals
Renewable energy: materials and processes Call: 2016
Senior Researcher : Manuel Moliner Marín Research Centre or Institution : Instituto de Tecnología Química. CSIC-Universidad Politécnica de Valencia. Call: 18th national competition for scientific and technical research
more information on Efficient materials for the capture and selective transformation of CO2 towards value-added chemicals
Heterogeneous biomimetic catalysts based on functionalized organic-inorganic hybrid networks to produce hydrogen
Renewable energy: materials and processes Call: 2016
Senior Researcher : Mª Dolores Esquivel Merino Research Centre or Institution : Instituto de Química Fina y Nanoquímica. Universidad de Córdoba. Call: 18th national competition for scientific and technical research
more information on Heterogeneous biomimetic catalysts based on functionalized organic-inorganic hybrid networks to produce hydrogen
Latent heat thermal energy storage by urea-based eutectic mixtures
Renewable energy: materials and processes Call: 2016
Senior Researcher : Álvaro Campos Celador Research Centre or Institution : Universidad del País Vasco (UPV-EHU). Call: 18th national competition for scientific and technical research
more information on Latent heat thermal energy storage by urea-based eutectic mixtures
Metal-organic frameworks as heterogeneous photocatalysts for CO2 reduction and H2 generation using H2O
Renewable energy: materials and processes Call: 2016
Senior Researcher : Sergio Navalón Oltra Research Centre or Institution : Departamento de Química. Universidad Politécnica de Valencia Call: 18th national competition for scientific and technical research
more information on Metal-organic frameworks as heterogeneous photocatalysts for CO2 reduction and H2 generation using H2O
Photoproduction of hydrogen with atomic quantum clusters using visible light
Renewable energy: materials and processes Call: 2016
Senior Researcher : Carlos Vázquez Vázquez Research Centre or Institution : Instituto de Investigaciones Tecnológicas. Laboratorio NANOMAG. Santiago de Compostela. Call: 18th national competition for scientific and technical research
more information on Photoproduction of hydrogen with atomic quantum clusters using visible light
Sunlight on nanocatalysts to lower global energy use, emissions and pollution
Renewable energy: materials and processes Call: 2016
Senior Researcher : María González Béjar Research Centre or Institution : Instituto de Ciencia Molecular. Universidad de Valencia. Call: 18th national competition for scientific and technical research
more information on Sunlight on nanocatalysts to lower global energy use, emissions and pollution

Tissue reprogramming and organoids

Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming
Tissue reprogramming and organoids Call: 2016
Senior Researcher : Antonio Baonza Cuenca Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid Call: 18th national competition for scientific and technical research
more information on Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming
Role of Purinergic signaling in human cortical development. A cerebral organoid-based approach
Tissue reprogramming and organoids Call: 2016
Senior Researcher : María Teresa Miras-Portugal Research Centre or Institution : Departamento de Bioquímica y Biología Molecular IV. Universidad Complutense. Madrid Call: 18th national competition for scientific and technical research
more information on Role of Purinergic signaling in human cortical development. A cerebral organoid-based approach

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