Research projects
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#Proyectos relacionados con Exosome optimisation for therapeutic use. The role of tetraspan in-rich micro domains in the biogenesis and function of exosomes
53 results. Displaying from 1 to 53
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Application of biomaterials with angiogenic, antioxidant and regenerative purposes in the central nervous system
2008
Senior Researcher : José Miguel Soria López Research Centre or Institution : Faculty of Health Sciences. CEU-Cardenal Herrera University. Valencia. (Spain) -
Immunity and atherosclerosis. New connections between the lipidic metabolism and microbial infections
2006
Senior Researcher : Antonio Castrillo Viguera Research Centre or Institution : Facultad de Medicina. Universidad de Las Palmas de Gran Canaria -
Implication of the bioactive sphingolipids in atherogenesis. Biophysical and cellular studies
2006
Senior Researcher : Félix Goñi Urcelay Research Centre or Institution : Unidad de Biofísica. Centro Mixto CSIC-UPV/EHU. Lejona. Vizcaya. -
Influence of genetic and pharmacological factors on innate immunity and immune response in the development of post-transplant arteriosclerosis
2006
Senior Researcher : José María Morales Cerdán Research Centre or Institution : Hospital Universitario 2 de Octubre. Madrid. -
New cellular and molecular mechanisms for regulating the atheroprotective protein p27 and possible diagnosis applications
2006
Senior Researcher : Vicente Andrés García Research Centre or Institution : Instituto de Biomedicina de Valencia. CSIC. -
New molecular markers for the formation and development of atherosclerotic plaques: Matrix metalloproteases (MT1-MMP and MT4-MMP) and regulating molecules (EMMPRIN)
2006
Senior Researcher : Alicia García Arroyo Research Centre or Institution : Centro Nacional de Investigaciones Cardiovasculares (CNIC). Madrid -
Relationship between sensitivity to insulin and the risk of atherosclerotic vascular disease: the European RISC Project
2006
Senior Researcher : Rafael Gabriel Sánchez Research Centre or Institution : Fundación para la Investigación Biomédica. Hospital Universitario La Paz. Madrid. -
Role of chemokines in differentiating monocytes from macrophage/spongy cells and reverse transendothelial migration, in the early stages of arteriosclerosis
2006
Senior Researcher : Paloma Sánchez-Mateos Rubio Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid -
Study of the biological role of the new atherosclerosis markers identified by proteomic analysis
2006
Senior Researcher : José Tuñón Fernández Research Centre or Institution : Fundación Jiménez Díaz. Madrid -
Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
2016
Senior Researcher : Fernando Rodríguez Serrano -
Characterization of infection biomarkers and possible drug targets present into exosome vesicles generated during in vitro and in vivo infection by Leishmania infantum
2016
Senior Researcher : Vicente Emilio Larraga Rodríguez de Vera Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC) -
Investigating the molecular mechanisms of exosome production under cellular stress
2016
Senior Researcher : Antonio Zorzano Olarte Research Centre or Institution : Instituto de Investigación Biomédica (IRB) Barcelona. -
Modulation of exosomes transporting miRNAs and lncRNAs for intercellular communication as therapeutic tools in dyslipidemia treatment
2016
Senior Researcher : Alberto Dávalos Herrera -
Study of EBV, HHV-6A AND HHV-6B MICRO-RNAs in plasma isolated exosomes of patients with multiple sclerosis: correlation with activity and progression of disease
2016
Senior Researcher : Roberto Álvarez Lafuente Research Centre or Institution : Hospital Universitario Clínico San Carlos. Instituto de Investigación Sanitaria San Carlos (IdISSC). Madrid. -
Exosomes: new intercellular communicators and their use as therapeutic agents in untreated parasitic diseases
2014
Senior Researcher : Hernando A. del Portillo Obando Research Centre or Institution : Centro de Investigación en Salud Internacional de Barcelona (CRESIB) -
Study of intracellular biogenesis and tissue bio-distribution of exosomes for the development of new therapeutic agents
2014
Senior Researcher : Juan Manuel Falcón Pérez Research Centre or Institution : Centro de Investigación Cooperativa en Biociencias (CIC bioGUNE) -
Production of second generation prebiotics and polyphenol glycosides. Validation of its bioactive properties for use in functional food
2018
Senior Researcher : María Fernández Lobato Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Using animal models for testing interventions targeting malnutrition and stunting in children
2016
Senior Researcher : Fernando Martín Belmonte Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Chicken embryonic stem cells. Study of the differentiation between somatic and germinal lineages and between mesodermic and endodermic lineages
2011
Senior Researcher : Federica Bertocchini Bertocchini Research Centre or Institution : IBBTEC-Universidad de Cantabria-CSIC. Santander. -
In vivo nuclear reprogramming and the functional interrelationship between p27 and SOX2
2011
Senior Researcher : Manuel Serrano Marugán Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Myosin II integrates the mechanical signals of the cellular micro-environment and controls the migration and differentiation of stem cells
2011
Senior Researcher : Miguel Vicente Manzanares Research Centre or Institution : Universidad Autónoma de Madrid. -
Nanotechnologically reprogrammed cellular medicines
2011
Senior Researcher : Marcos García Fuentes Research Centre or Institution : Centro Singular en Medicina Molecular y Enfermedades Crónicas. Universidad de Santiago de Compostelamore information on Nanotechnologically reprogrammed cellular medicines
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Study of the neuroprotector capacity of the epithelial cells of the choroid plexi as a potential regenerative therapy for Alzheimer's disease
2011
Senior Researcher : Eva María Carro Díaz Research Centre or Institution : Instituto de Investigación Hospital 2 de Octubre. Madrid. -
The generation of iPSC cells for the study of neurodevelopmental diseases: autism and William's syndrome
2011
Senior Researcher : Ivon Cuscó Martí Research Centre or Institution : Centros de Investigación Biomédica en Red (CIBER)-Universidad Pompeu Fabra. Barcelona -
The subarachnoid administration of previously cryopreserved allogenic stromal cells in traumatic spinal lesion
2011
Senior Researcher : Mercedes Zurita Castillo Research Centre or Institution : Hospital Universitario Puerta de Hierro Majadahonda. Madrid. -
Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
2016
Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators
2016
Senior Researcher : Yolanda Revilla Novella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons
2016
Senior Researcher : María Jesús Bullido Gómez-Heras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
New functional complexes deriving from the interaction of Gaq with proteins that contain PB1 domains, and the possible repercussion of this in cardiovascular pathologies
2014
Senior Researcher : Catalina Ribas Núñez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Study of the tissue-specific interactome of the GRK2 node involved in insulin resistance and obesity: pathological repercussions
2014
Senior Researcher : Cristina Murga Montesinos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Comprehensive virus-host protein interactome by the use of yeast-two-hybrid coupled to next-generation sequencing analysis
2018
Senior Researcher : Margarita Salas Falgueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Interactome rewiring by phosphorylation and acetylation barcodes: implications in metabolic reprogramming in breast cancer
2018
Senior Researcher : Federico Mayor Menéndez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Studies of tumorigenesis in Drosophila: possible clinical implications
2014
Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Studies of tumorigenesis in Drosophila: possible clinical implications
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The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
2014
Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
2014
Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
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Functional characterisation of the eIF2alpha, GCN2 and PERK kinases in the molecular memory mechanisms
2006
Senior Researcher : César de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis
2018
Senior Researcher : Héctor Peinado Selgas Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine
2018
Senior Researcher : José Fernández Piqueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Novel immunotherapeutic strategies against T-ALL, a rare pediatric disease
2018
Senior Researcher : María Luisa Toribio García Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Novel immunotherapeutic strategies against T-ALL, a rare pediatric disease
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AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies
2016
Senior Researcher : Jorgina Satrústegui Gil-Delgado Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
2016
Senior Researcher : César Cobaleda Hernández Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
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Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases
2016
Senior Researcher : Paola Bovolenta Nicolao Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Genome and transcriptome analysis to identify splicing defects and in vivo evaluation of antisense therapy
2014
Senior Researcher : Lourdes Ruiz Desviat Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Molecular mechanisms in Dravet's syndrome
2014
Senior Researcher : Francisco Zafra Gómez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Molecular mechanisms in Dravet's syndrome
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Study of the functional implications of GRK2 serine-threonine kinase in Hereditary Haemorrhagic Telangiectasia
2011
Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The molecular bases for variability in the presentation and clinical development of Wilson's disease
2011
Senior Researcher : Ignacio Vicente-Sandoval Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Alternative therapies for inherited metabolic diseases
2008
Senior Researcher : Alejandra Gámez Abascal Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Alternative therapies for inherited metabolic diseases
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Analysis using genetically modified mice of the possible role of alpha-synuclein in the pathogenesis of Huntington's disease
2008
Senior Researcher : José Javier Lucas Lozano Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Molecular and cellular bases of mental retardation associated with "Fragile X" syndrome
2008
Senior Researcher : José Antonio Esteban García Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Epigenetic control of cell differentiation and pluripotency by BRAF35 AND iBRAF proteins
2008
Senior Researcher : José Carlos Reyes Rosa Research Centre or Institution : Centro Andaluz de Biología Molecular y Medicina Regenerativa (CSIC) -
Transcription factors and heterochromatin formation in Drosophila
2008
Senior Researcher : Natalia Azpiazu Torres Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Transcription factors and heterochromatin formation in Drosophila
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Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming
2016
Senior Researcher : Antonio Baonza Cuenca Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Role of Purinergic signaling in human cortical development. A cerebral organoid-based approach
2016
Senior Researcher : María Teresa Miras-Portugal Research Centre or Institution : Departamento de Bioquímica y Biología Molecular IV. Universidad Complutense. Madrid
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