Research projects
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#Proyectos relacionados con The structural bases of tumoral development associated with transcription regulating interactome defects
46 results. Displaying from 1 to 46
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Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes
2008
Senior Researcher : Manuel Arruebo Gordo Research Centre or Institution : Institute of Nanoscience of Aragón. University of Zaragoza. -
Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
2016
Senior Researcher : Fernando Rodríguez Serrano -
The elimination of endocrine disruptors to improve food security
2014
Senior Researcher : José Luis García López Research Centre or Institution : Centro de Investigaciones Biológicas (CIB) (CSIC)more information on The elimination of endocrine disruptors to improve food security
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Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations
2006
Senior Researcher : Francisco Barros Angueira Research Centre or Institution : Hospital Clínico Universitario de Santiago de Compostela. Fundación Pública Galega de Medicina Xenómica. -
Pharmacogenetics in colorectal cancer
2006
Senior Researcher : Luis Andrés López Fernández Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid -
Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)
2018
Senior Researcher : Alejandro Gómez Roca Research Centre or Institution : Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona. -
Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
2016
Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
2016
Senior Researcher : Eva Martín del Valle Research Centre or Institution : Universidad de Salamanca -
Development of new targets for immunotherapy in cancer metastasis
2016
Senior Researcher : José Ignacio Casal Álvarez Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)more information on Development of new targets for immunotherapy in cancer metastasis
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From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
2016
Senior Researcher : Enrique María Ocio San Miguel -
Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
2016
Senior Researcher : Juan José Lasarte Sagastibelza -
Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
2016
Senior Researcher : Ángel Carracedo Álvarez Research Centre or Institution : Fundación Pública Gallega de Medicina Genómica. Santiago de Compostela. -
The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
2016
Senior Researcher : Carlos Martínez Alonso Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid -
Transforming EGFR expressing tumors into immune-rejectable tissues
2016
Senior Researcher : Fernando Pastor Rodríguezmore information on Transforming EGFR expressing tumors into immune-rejectable tissues
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Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators
2016
Senior Researcher : Yolanda Revilla Novella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Identification of the nucleotide cellular sensor and its interactome
2016
Senior Researcher : Marçal Pastor Anglada Research Centre or Institution : CIBEREHD - Universidad de Barcelonamore information on Identification of the nucleotide cellular sensor and its interactome
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Interactions of the protein N-acetylglucosamine kinase with different elements of gene regulation in Yarrowia lipolytica
2016
Senior Researcher : Carlos Gancedo Rodríguez Research Centre or Institution : Instituto de Investigaciones Biomédicas "Alberto Sols". CSIC-Universidad Autónoma de Madrid. -
Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons
2016
Senior Researcher : María Jesús Bullido Gómez-Heras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
WIP differential interactome during its oncogenic or tumor suppressor activity
2016
Senior Researcher : Inés María Antón Gutiérrez Research Centre or Institution : CIBERNED/CNB-CSIC. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas-Centro Nacional de Biotecnología. Madridmore information on WIP differential interactome during its oncogenic or tumor suppressor activity
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New functional complexes deriving from the interaction of Gaq with proteins that contain PB1 domains, and the possible repercussion of this in cardiovascular pathologies
2014
Senior Researcher : Catalina Ribas Núñez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Photoselective inhibition of protein-protein interactions to study interactomic networks and the development of new therapies
2014
Senior Researcher : Pau Gorostiza Langa Research Centre or Institution : Instituto de Bioingeniería de Cataluña (IBEC). Barcelona. -
Study of the tissue-specific interactome of the GRK2 node involved in insulin resistance and obesity: pathological repercussions
2014
Senior Researcher : Cristina Murga Montesinos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The molecular bases of disease: biointeractomics of programmed cell death
2014
Senior Researcher : Miguel Ángel De la Rosa Acosta Research Centre or Institution : cicCartuja, Instituto de Bioquímica Vegetal y Fotosíntesis. Universidad de Sevilla-CSICmore information on The molecular bases of disease: biointeractomics of programmed cell death
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Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence
2020
Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular Severo Ochoa. CSIC - UAM -
Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma
2014
Senior Researcher : José Ángel Martínez-Climent Research Centre or Institution : Centro de Investigación Médica Aplicada de la Universidad de Navarra -
Molecular characterisation of the role of mitochondrial dysfunction in tumoral development
2014
Senior Researcher : Ignacio Alejandro Varela Egocheaga Research Centre or Institution : Instituto de Biomedicina y Biotecnología de Cantabria. CSIC-Universidad de Cantabria-SODERCAN. -
Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies
2014
Senior Researcher : Ángel Hernández Hernández Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca. -
Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer
2014
Senior Researcher : Xosé Ramón García Bustelo Research Centre or Institution : Centro de Investigación del Cáncer de Salamanca -
Studies of tumorigenesis in Drosophila: possible clinical implications
2014
Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Studies of tumorigenesis in Drosophila: possible clinical implications
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The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas
2014
Senior Researcher : Rosa Mª Señarís Rodríguez Research Centre or Institution : Departamento de Fisiología. CIMUS. Universidad de Santiago de Compostela -
The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
2014
Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The diagnosis of cancer by means of a metabolic nanosensor platform
2014
Senior Researcher : Ángel Orte Gutiérrez Research Centre or Institution : Facultad de Farmacia. Universidad de Granadamore information on The diagnosis of cancer by means of a metabolic nanosensor platform
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The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells
2014
Senior Researcher : Aránzazu Tabernero Urbieta Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca. -
The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer
2014
Senior Researcher : Teresa Puig Miquel Research Centre or Institution : Facultad de Medicina. Universidad de Girona -
The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
2014
Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
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Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination
2020
Senior Researcher : Eva Ortega Paíno Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)
2020
Senior Researcher : Nuria Malats Riera y Ravid Straussman Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot -
p38α in control of UV-induced melanoma development and progression
2018
Senior Researcher : Juan Ángel Recio Conde Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelonamore information on p38α in control of UV-induced melanoma development and progression
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Precision medicine approach to target deregulated metabolism in multiple myeloma
2018
Senior Researcher : Francisco Javier Planes Pedreño Research Centre or Institution : TECNUN, Escuela de Ingenieros de la Universidad de Navarramore information on Precision medicine approach to target deregulated metabolism in multiple myeloma
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Dyskeratosis congenita. New models, New molecular keys and New treatments
2016
Senior Researcher : María Luisa Cayuela Fuentes Research Centre or Institution : Hospital Clínico Universitario Virgen de la Arrixaca. Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca. El Palmar, Murcia.more information on Dyskeratosis congenita. New models, New molecular keys and New treatments
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Visualisation of neuronal polysomal architecture and its alterations in Huntington's Disease
2016
Senior Researcher : José Jesús Fernández Rodríguez Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid -
Analysis of the contribution of CRB2 protein to the establishment and permanence of adherent joins in the pigmentary epithelium, and its relationship with retinal dystrophies
2011
Senior Researcher : Mª Concepción Lillo Delgado Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca. -
Pathological mechanisms in Lysinuria with protein intolerance
2011
Senior Researcher : Manuel Palacín Prieto Research Centre or Institution : Instituto de Investigación Biomédica (IRB) Barcelona.more information on Pathological mechanisms in Lysinuria with protein intolerance
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Study of the regulation of protein PSTPIP1 via tyrosine phosphorylation and its contribution to the aetiology of the PAPA autoinflammatory disease
2008
Senior Researcher : Andrés Alonso García Research Centre or Institution : Instituto de Biología y Genética Molecular. CSIC. Valladolid. -
Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype
2006
Senior Researcher : Carlos Pipaón González Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander. -
Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system
2008
Senior Researcher : Miguel Ángel Vidal Caballero Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)
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