Research projects
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#Proyectos relacionados con New functional complexes deriving from the interaction of Gaq with proteins that contain PB1 domains, and the possible repercussion of this in cardiovascular pathologies
39 results. Displaying from 1 to 39
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Exosome optimisation for therapeutic use. The role of tetraspan in-rich micro domains in the biogenesis and function of exosomes
2014
Senior Researcher : María Yáñez Mó Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Production of second generation prebiotics and polyphenol glycosides. Validation of its bioactive properties for use in functional food
2018
Senior Researcher : María Fernández Lobato Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Using animal models for testing interventions targeting malnutrition and stunting in children
2016
Senior Researcher : Fernando Martín Belmonte Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
2016
Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators
2016
Senior Researcher : Yolanda Revilla Novella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Identification of the nucleotide cellular sensor and its interactome
2016
Senior Researcher : Marçal Pastor Anglada Research Centre or Institution : CIBEREHD - Universidad de Barcelonamore information on Identification of the nucleotide cellular sensor and its interactome
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Interactions of the protein N-acetylglucosamine kinase with different elements of gene regulation in Yarrowia lipolytica
2016
Senior Researcher : Carlos Gancedo Rodríguez Research Centre or Institution : Instituto de Investigaciones Biomédicas "Alberto Sols". CSIC-Universidad Autónoma de Madrid. -
Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons
2016
Senior Researcher : María Jesús Bullido Gómez-Heras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
WIP differential interactome during its oncogenic or tumor suppressor activity
2016
Senior Researcher : Inés María Antón Gutiérrez Research Centre or Institution : CIBERNED/CNB-CSIC. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas-Centro Nacional de Biotecnología. Madridmore information on WIP differential interactome during its oncogenic or tumor suppressor activity
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Photoselective inhibition of protein-protein interactions to study interactomic networks and the development of new therapies
2014
Senior Researcher : Pau Gorostiza Langa Research Centre or Institution : Instituto de Bioingeniería de Cataluña (IBEC). Barcelona. -
Study of the tissue-specific interactome of the GRK2 node involved in insulin resistance and obesity: pathological repercussions
2014
Senior Researcher : Cristina Murga Montesinos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The molecular bases of disease: biointeractomics of programmed cell death
2014
Senior Researcher : Miguel Ángel De la Rosa Acosta Research Centre or Institution : cicCartuja, Instituto de Bioquímica Vegetal y Fotosíntesis. Universidad de Sevilla-CSICmore information on The molecular bases of disease: biointeractomics of programmed cell death
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The structural bases of tumoral development associated with transcription regulating interactome defects
2014
Senior Researcher : Carlos Fernández Tornero Research Centre or Institution : Centro de Investigaciones Biológicas (CIB) (CSIC) -
Comprehensive virus-host protein interactome by the use of yeast-two-hybrid coupled to next-generation sequencing analysis
2018
Senior Researcher : Margarita Salas Falgueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Interactome rewiring by phosphorylation and acetylation barcodes: implications in metabolic reprogramming in breast cancer
2018
Senior Researcher : Federico Mayor Menéndez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma
2014
Senior Researcher : José Ángel Martínez-Climent Research Centre or Institution : Centro de Investigación Médica Aplicada de la Universidad de Navarra -
Studies of tumorigenesis in Drosophila: possible clinical implications
2014
Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Studies of tumorigenesis in Drosophila: possible clinical implications
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The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
2014
Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
2014
Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
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Functional characterisation of the eIF2alpha, GCN2 and PERK kinases in the molecular memory mechanisms
2006
Senior Researcher : César de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis
2018
Senior Researcher : Héctor Peinado Selgas Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine
2018
Senior Researcher : José Fernández Piqueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Novel immunotherapeutic strategies against T-ALL, a rare pediatric disease
2018
Senior Researcher : María Luisa Toribio García Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Novel immunotherapeutic strategies against T-ALL, a rare pediatric disease
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AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies
2016
Senior Researcher : Jorgina Satrústegui Gil-Delgado Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
2016
Senior Researcher : César Cobaleda Hernández Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
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Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases
2016
Senior Researcher : Paola Bovolenta Nicolao Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Visualisation of neuronal polysomal architecture and its alterations in Huntington's Disease
2016
Senior Researcher : José Jesús Fernández Rodríguez Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid -
Genome and transcriptome analysis to identify splicing defects and in vivo evaluation of antisense therapy
2014
Senior Researcher : Lourdes Ruiz Desviat Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Molecular mechanisms in Dravet's syndrome
2014
Senior Researcher : Francisco Zafra Gómez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Molecular mechanisms in Dravet's syndrome
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Analysis of the contribution of CRB2 protein to the establishment and permanence of adherent joins in the pigmentary epithelium, and its relationship with retinal dystrophies
2011
Senior Researcher : Mª Concepción Lillo Delgado Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca. -
Pathological mechanisms in Lysinuria with protein intolerance
2011
Senior Researcher : Manuel Palacín Prieto Research Centre or Institution : Instituto de Investigación Biomédica (IRB) Barcelona.more information on Pathological mechanisms in Lysinuria with protein intolerance
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Study of the functional implications of GRK2 serine-threonine kinase in Hereditary Haemorrhagic Telangiectasia
2011
Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The molecular bases for variability in the presentation and clinical development of Wilson's disease
2011
Senior Researcher : Ignacio Vicente-Sandoval Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Alternative therapies for inherited metabolic diseases
2008
Senior Researcher : Alejandra Gámez Abascal Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Alternative therapies for inherited metabolic diseases
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Analysis using genetically modified mice of the possible role of alpha-synuclein in the pathogenesis of Huntington's disease
2008
Senior Researcher : José Javier Lucas Lozano Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Molecular and cellular bases of mental retardation associated with "Fragile X" syndrome
2008
Senior Researcher : José Antonio Esteban García Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Study of the regulation of protein PSTPIP1 via tyrosine phosphorylation and its contribution to the aetiology of the PAPA autoinflammatory disease
2008
Senior Researcher : Andrés Alonso García Research Centre or Institution : Instituto de Biología y Genética Molecular. CSIC. Valladolid. -
Transcription factors and heterochromatin formation in Drosophila
2008
Senior Researcher : Natalia Azpiazu Torres Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Transcription factors and heterochromatin formation in Drosophila
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Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming
2016
Senior Researcher : Antonio Baonza Cuenca Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid
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