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Research projects
#Proyectos relacionados con Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations
89 results. Displaying from 1 to 89
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Azotobacter vinelandii as bio-factories for producing hydrogen
2008
Senior Researcher : Juan Imperial Ródenas Research Centre or Institution : Centro de Biotecnología y Genómica de Plantas. Universidad Politécnica de Madridmore information on Azotobacter vinelandii as bio-factories for producing hydrogen
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H2 production from glycerol with the aid of microbial cells isolated from the extremophile ecosystem of Rio Tinto
2008
Senior Researcher : Víctor Manuel Fernández López Research Centre or Institution : Instituto de Catálisis y Petroleoquímica. CSIC. Madrid. -
Using genetic engineering to obtain strains of Clostridium cellulolyticum and Rhodobacter capsulatus that overproduce hydrogen
2008
Senior Researcher : Alberto Sola Landa Research Centre or Institution : Instituto de Biotecnología de León (INBIOTEC). -
The intracellular administration of drugs controlled by biomimetic nano-injectors
2011
Senior Researcher : Miguel Ángel Correa Duarte Research Centre or Institution : Universidad de Vigo. -
Design of new dosage forms for oral administration of immunotherapy for the treatment of food allergy to peanuts
2008
Senior Researcher : Marta Ferrer Puga Research Centre or Institution : University Clinic of Navarra. University of Navarra. (Spain). -
Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes
2008
Senior Researcher : Manuel Arruebo Gordo Research Centre or Institution : Institute of Nanoscience of Aragón. University of Zaragoza. -
Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. Rescue of the phenotype and cell transplantation
2016
Senior Researcher : Carlos Vicario Abejón Research Centre or Institution : Instituto Cajal. CSIC. Madrid. -
Influence of genetic and pharmacological factors on innate immunity and immune response in the development of post-transplant arteriosclerosis
2006
Senior Researcher : José María Morales Cerdán Research Centre or Institution : Hospital Universitario 2 de Octubre. Madrid. -
Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
2016
Senior Researcher : Fernando Rodríguez Serrano -
Cellular therapy for West's syndrome
2011
Senior Researcher : Manuel Álvarez Dolado Research Centre or Institution : CABIMER. CSIC -
Chicken embryonic stem cells. Study of the differentiation between somatic and germinal lineages and between mesodermic and endodermic lineages
2011
Senior Researcher : Federica Bertocchini Bertocchini Research Centre or Institution : IBBTEC-Universidad de Cantabria-CSIC. Santander. -
Epigenetic study in vivo of the role of retinoic acid in the regeneration of ciliate cells
2011
Senior Researcher : Berta Alsina Español Research Centre or Institution : Universidad Pompeu Fabra-PRBB. Barcelona. -
In vivo nuclear reprogramming and the functional interrelationship between p27 and SOX2
2011
Senior Researcher : Manuel Serrano Marugán Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Myosin II integrates the mechanical signals of the cellular micro-environment and controls the migration and differentiation of stem cells
2011
Senior Researcher : Miguel Vicente Manzanares Research Centre or Institution : Universidad Autónoma de Madrid. -
Nanotechnologically reprogrammed cellular medicines
2011
Senior Researcher : Marcos García Fuentes Research Centre or Institution : Centro Singular en Medicina Molecular y Enfermedades Crónicas. Universidad de Santiago de Compostelamore information on Nanotechnologically reprogrammed cellular medicines
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Study of the neuroprotector capacity of the epithelial cells of the choroid plexi as a potential regenerative therapy for Alzheimer's disease
2011
Senior Researcher : Eva María Carro Díaz Research Centre or Institution : Instituto de Investigación Hospital 2 de Octubre. Madrid. -
The generation of iPSC cells for the study of neurodevelopmental diseases: autism and William's syndrome
2011
Senior Researcher : Ivon Cuscó Martí Research Centre or Institution : Centros de Investigación Biomédica en Red (CIBER)-Universidad Pompeu Fabra. Barcelona -
The subarachnoid administration of previously cryopreserved allogenic stromal cells in traumatic spinal lesion
2011
Senior Researcher : Mercedes Zurita Castillo Research Centre or Institution : Hospital Universitario Puerta de Hierro Majadahonda. Madrid. -
Clinical genetic studies of a cohort with hereditary Alzheimer's disease (new locus)
2006
Senior Researcher : Adriano Jiménez Escrig Research Centre or Institution : Fundación para la Investigación Biomédica. Hospital Universitario Ramón y Cajal. Madrid. -
Geno-tPA: Search for predictive genetic patterns for the progress of patients with ischemic ictus following treatment with t-PA
2006
Senior Researcher : Joan Montaner Villalonga Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelona -
Genomic research in patients with an initial schizophrenic episode: identification of genetic and pharmacogenetic markers
2006
Senior Researcher : Benedicto Crespo-Facorro Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander. -
Implications of mevalonic acid, Wnt and oestrogen pathways in osteoporosis and response to antiresorptive drugs
2006
Senior Researcher : José A. Riancho Moral Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander. -
Intestinal inflammatory diseases: susceptibility and pharmacogenetic markers
2006
Senior Researcher : María Elena Urcelay García Research Centre or Institution : Hospital Universitario Clínico San Carlos. Madrid.more information on Intestinal inflammatory diseases: susceptibility and pharmacogenetic markers
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Pharmacogenetics in colorectal cancer
2006
Senior Researcher : Luis Andrés López Fernández Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid -
Search for differential genetic markers between two different types of response to the same allergenic exposure: tolerance versus sensitisation
2006
Senior Researcher : Blanca Cárdaba Olombrada Research Centre or Institution : Fundación Jiménez Díaz. Madrid -
Study of the impact of genetic polymorphisms in the toxicity of the antiretroviral drugs used to treat HIV
2006
Senior Researcher : Sonia María Rodríguez Nóvoa Research Centre or Institution : Hospital Carlos III. Madrid. -
Taxane pharmacogenetics: neurotoxicity and therapeutic efficacy
2006
Senior Researcher : Cristina Rodríguez González de Antona Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madridmore information on Taxane pharmacogenetics: neurotoxicity and therapeutic efficacy
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Transportome as a predictive response element: the importance of nucleoside transporters
2006
Senior Researcher : Francisco Javier Casado Merediz Research Centre or Institution : Facultad de Biología. Universidad de Barcelona -
Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)
2018
Senior Researcher : Alejandro Gómez Roca Research Centre or Institution : Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona. -
Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
2016
Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
2016
Senior Researcher : Eva Martín del Valle Research Centre or Institution : Universidad de Salamanca -
Development of new targets for immunotherapy in cancer metastasis
2016
Senior Researcher : José Ignacio Casal Álvarez Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)more information on Development of new targets for immunotherapy in cancer metastasis
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From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
2016
Senior Researcher : Enrique María Ocio San Miguel -
Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
2016
Senior Researcher : Juan José Lasarte Sagastibelza -
Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
2016
Senior Researcher : Ángel Carracedo Álvarez Research Centre or Institution : Fundación Pública Gallega de Medicina Genómica. Santiago de Compostela. -
The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
2016
Senior Researcher : Carlos Martínez Alonso Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid -
Transforming EGFR expressing tumors into immune-rejectable tissues
2016
Senior Researcher : Fernando Pastor Rodríguezmore information on Transforming EGFR expressing tumors into immune-rejectable tissues
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The structural bases of tumoral development associated with transcription regulating interactome defects
2014
Senior Researcher : Carlos Fernández Tornero Research Centre or Institution : Centro de Investigaciones Biológicas (CIB) (CSIC) -
Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence
2020
Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular Severo Ochoa. CSIC - UAM -
Application of genetic analyses for the creation of germplasm banks in teleostei
2008
Senior Researcher : Vanesa Robles Rodríguez Research Centre or Institution : Departamento de Biología Molecular e Instituto de Desarrollo Ganadero y Sanidad Animal (INDEGSAL). Universidad de Leónmore information on Application of genetic analyses for the creation of germplasm banks in teleostei
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Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma
2014
Senior Researcher : José Ángel Martínez-Climent Research Centre or Institution : Centro de Investigación Médica Aplicada de la Universidad de Navarra -
Molecular characterisation of the role of mitochondrial dysfunction in tumoral development
2014
Senior Researcher : Ignacio Alejandro Varela Egocheaga Research Centre or Institution : Instituto de Biomedicina y Biotecnología de Cantabria. CSIC-Universidad de Cantabria-SODERCAN. -
Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies
2014
Senior Researcher : Ángel Hernández Hernández Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca. -
Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer
2014
Senior Researcher : Xosé Ramón García Bustelo Research Centre or Institution : Centro de Investigación del Cáncer de Salamanca -
Studies of tumorigenesis in Drosophila: possible clinical implications
2014
Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Studies of tumorigenesis in Drosophila: possible clinical implications
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The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas
2014
Senior Researcher : Rosa Mª Señarís Rodríguez Research Centre or Institution : Departamento de Fisiología. CIMUS. Universidad de Santiago de Compostela -
The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
2014
Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The diagnosis of cancer by means of a metabolic nanosensor platform
2014
Senior Researcher : Ángel Orte Gutiérrez Research Centre or Institution : Facultad de Farmacia. Universidad de Granadamore information on The diagnosis of cancer by means of a metabolic nanosensor platform
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The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells
2014
Senior Researcher : Aránzazu Tabernero Urbieta Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca. -
The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer
2014
Senior Researcher : Teresa Puig Miquel Research Centre or Institution : Facultad de Medicina. Universidad de Girona -
The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
2014
Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
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Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination
2020
Senior Researcher : Eva Ortega Paíno Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)
2020
Senior Researcher : Nuria Malats Riera y Ravid Straussman Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot -
p38α in control of UV-induced melanoma development and progression
2018
Senior Researcher : Juan Ángel Recio Conde Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelonamore information on p38α in control of UV-induced melanoma development and progression
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Precision medicine approach to target deregulated metabolism in multiple myeloma
2018
Senior Researcher : Francisco Javier Planes Pedreño Research Centre or Institution : TECNUN, Escuela de Ingenieros de la Universidad de Navarramore information on Precision medicine approach to target deregulated metabolism in multiple myeloma
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Dyskeratosis congenita. New models, New molecular keys and New treatments
2016
Senior Researcher : María Luisa Cayuela Fuentes Research Centre or Institution : Hospital Clínico Universitario Virgen de la Arrixaca. Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca. El Palmar, Murcia.more information on Dyskeratosis congenita. New models, New molecular keys and New treatments
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Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
2016
Senior Researcher : César Cobaleda Hernández Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)
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The function of the E3 ubiquitin ligase APC/C-Cdh1 in Fragile X Syndrome. Possible therapeutic application
2016
Senior Researcher : Ángeles Almeida Parra Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca. -
Identification of the function of the Wt1gene in Huntington's disease
2014
Senior Researcher : Ofelia M. Martínez Estrada Research Centre or Institution : Departamento de Biología Celular. Universidad de Barcelonamore information on Identification of the function of the Wt1gene in Huntington's disease
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Models for congenital muscular dystrophies: the search for phenotype suppressors
2014
Senior Researcher : Enrique Martín Blanco Research Centre or Institution : Instituto de Biología Molecular de Barcelona. CSIC.more information on Models for congenital muscular dystrophies: the search for phenotype suppressors
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Hereditary metabolic diseases: searching for new genes that cause diseases and research into new therapeutic strategies
2011
Senior Researcher : Mª del Pilar Rodríguez Pombo Research Centre or Institution : Universidad Autónoma de Madrid. -
Study of the functional implications of GRK2 serine-threonine kinase in Hereditary Haemorrhagic Telangiectasia
2011
Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
The complete sequencing of the exomic genome of systemic lupus erythematosus in families of European origin with multiple cases: the identification of rare mutations and their functional consequences
2011
Senior Researcher : Marta Eugenia Alarcón Riquelme Research Centre or Institution : Centro Pfizer. Universidad de Granada. Junta de Andalucía de Genómica e Investigación Oncológica (GENYO). Granada -
The identification of new genes responsible for Hereditary Dystrophies of the Retina using Next-Generation Sequencing technology and the determination of associated pathogenic mechanisms
2011
Senior Researcher : Guillermo Antiñolo Gil Research Centre or Institution : Hospital Universitario Virgen del Rocío. Sevilla. -
Alternative therapies for inherited metabolic diseases
2008
Senior Researcher : Alejandra Gámez Abascal Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Alternative therapies for inherited metabolic diseases
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Analysis using genetically modified mice of the possible role of alpha-synuclein in the pathogenesis of Huntington's disease
2008
Senior Researcher : José Javier Lucas Lozano Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Genetic and cellular basis of 16p11.2-p12.2 microdeletion syndrome and related neural disorders
2008
Senior Researcher : Marcos Malumbres Martínez Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Testing xenoexpression as gene therapy for mitochondrial diseases
2008
Senior Researcher : Patricio Fernández Silva Research Centre or Institution : Facultad de Veterinaria. Universidad de Zaragozamore information on Testing xenoexpression as gene therapy for mitochondrial diseases
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Study of the molecular foundations of congenital malformations: cardiovascular, oculofacial and skeletal
2006
Senior Researcher : María José Trujillo Tiebas Research Centre or Institution : Fundación Jiménez Díaz. Madrid -
Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype
2006
Senior Researcher : Carlos Pipaón González Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander. -
Extracellular vesicles biomarkers for the diagnosis and prognosis of post-surgical septic shock
2018
Senior Researcher : Eduardo Tamayo Gómez Research Centre or Institution : Hospital Clínico Universitario de Valladolid -
Risk Assesment of Bacterial Sepsis using multiomic and bioinformatics tools: an approach towards the Precision Medicine in Infectious Diseases
2018
Senior Researcher : María Teresa Coque González -
Synthetic nanoparticles as an innovative treatment for sepsis (SPRINT-4-SEPSIS)
2018
Senior Researcher : Antonio Artigas Raventós Research Centre or Institution : Instituto de Investigación e Innovación Parc Taulí (I3PT), Corporación Sanitaria i Universitaria Parc Taulímore information on Synthetic nanoparticles as an innovative treatment for sepsis (SPRINT-4-SEPSIS)
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Epigenetic alterations in tetraploid neurones and Alzheimer's disease
2011
Senior Researcher : José María Frade López Research Centre or Institution : Instituto Cajal. CSIC. Madrid.more information on Epigenetic alterations in tetraploid neurones and Alzheimer's disease
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Epigenome and transcriptome of nociception (Functional epigenomics of nociception)
2011
Senior Researcher : Ángel Manuel Carrión Rodríguez Research Centre or Institution : Facultad de Ciencias Experimentales. Universidad Pablo de Olavide. Sevilla -
Experimental study of the epigenetic implications of changes in the composition of fatty acids in the diet during pregnancy and their consequences for adult offspring
2011
Senior Researcher : Emilio Herrera Castillón Research Centre or Institution : Universidad San Pablo-CEU. Madrid. -
Nutri-epigenetics of the control of body adiposity: studies in animal models of differing susceptibility to obesity based on nutritional interventions in early stages in life
2011
Senior Researcher : María Luisa Bonet Piña Research Centre or Institution : Universidad de las Islas Baleares. Mallorca -
Study of the methylome/genome relationship and their points in common in systemic autoimmune diseases: SLE, RA and SSc
2011
Senior Researcher : Esteban Ballestar Tarín Research Centre or Institution : Instituto de Investigación Biomédica de Bellvitge (IDIBELL). Barcelona. -
The acetylomes of neural differentiation
2011
Senior Researcher : Mario Fernández Fraga Research Centre or Institution : Instituto Universitario de Oncología del Principado de Asturias (IUOPA)-Universidad de Oviedo.more information on The acetylomes of neural differentiation
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The epigenetic regulation of reelin in Alzheimer's disease
2011
Senior Researcher : Javier Sáez Valero Research Centre or Institution : Instituto de Neurociencias. CSIC-Universidad Miguel Hernández. Alicante.more information on The epigenetic regulation of reelin in Alzheimer's disease
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Association between non-coding RNAs in ultra-conserved regions (T-UCR) and the epigenome: involvement in cancer
2008
Senior Researcher : Manel Esteller Badosa Research Centre or Institution : Epigenetics and Cancer Biology Program. Bellvitge Biomedical Research Institute (IDIBELL). Barcelona. (Spain) -
Epigenetic control of cell differentiation and pluripotency by BRAF35 AND iBRAF proteins
2008
Senior Researcher : José Carlos Reyes Rosa Research Centre or Institution : Centro Andaluz de Biología Molecular y Medicina Regenerativa (CSIC) -
Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system
2008
Senior Researcher : Miguel Ángel Vidal Caballero Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC) -
Epigenetic regulation of the maintenance of genomic stability during mitotic and meiotic cell cycle
2008
Senior Researcher : Pedro Antonio San Segundo Nieto Research Centre or Institution : Instituto de Microbiología Bioquímica. CSIC-Universidad de Salamanca. -
High resolution profiles of acetylation and methylation of histones in the epigenome of Arabidopsis thaliana: functional connection with the biological clock
2008
Senior Researcher : Paloma Más Martínez Research Centre or Institution : Consorcio CSIC-IRTA-UAB. Centro de Investigación en Agrigenómica (CRAG). Barcelona -
Role of epigenetic mechanisms in the processes of learning and memory
2008
Senior Researcher : Ángel Manuel Carrión Rodríguez Research Centre or Institution : Faculty of Experimental Sciences. Pablo de Olavide University. Sevillamore information on Role of epigenetic mechanisms in the processes of learning and memory
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Search and identification of new genetic and epigenetic causes of autistic spectrum disorders: design and implementation of a targeted high-resolution array with key elements of the epigenetic machinery
2008
Senior Researcher : María del Carmen Orellana Alonso Research Centre or Institution : Hospital Universitario La Fe. Valencia. -
Transcription factors and heterochromatin formation in Drosophila
2008
Senior Researcher : Natalia Azpiazu Torres Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Transcription factors and heterochromatin formation in Drosophila
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Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming
2016
Senior Researcher : Antonio Baonza Cuenca Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid