List of projects - Fundación Ramón Areces

Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)

2020

Senior Researcher : Nuria Malats Riera y Ravid Straussman Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot

more information on Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)

Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination

2020

Senior Researcher : Eva Ortega Paíno Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid

more information on Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination

Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence

2020

Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular Severo Ochoa. CSIC - UAM

more information on Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence

Precision medicine approach to target deregulated metabolism in multiple myeloma

2018

Senior Researcher : Francisco Javier Planes Pedreño Research Centre or Institution : TECNUN, Escuela de Ingenieros de la Universidad de Navarra

more information on Precision medicine approach to target deregulated metabolism in multiple myeloma

p38α in control of UV-induced melanoma development and progression

2018

Senior Researcher : Juan Ángel Recio Conde Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelona

more information on p38α in control of UV-induced melanoma development and progression

Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)

2018

Senior Researcher : Alejandro Gómez Roca Research Centre or Institution : Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona.

more information on Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)

Dyskeratosis congenita. New models, New molecular keys and New treatments

2016

Senior Researcher : María Luisa Cayuela Fuentes Research Centre or Institution : Hospital Clínico Universitario Virgen de la Arrixaca. Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca. El Palmar, Murcia.

more information on Dyskeratosis congenita. New models, New molecular keys and New treatments

Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC

2016

Senior Researcher : Ángel Carracedo Álvarez Research Centre or Institution : Fundación Pública Gallega de Medicina Genómica. Santiago de Compostela.

more information on Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC

Development of new targets for immunotherapy in cancer metastasis

2016

Senior Researcher : José Ignacio Casal Álvarez Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)

more information on Development of new targets for immunotherapy in cancer metastasis

Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy

2016

Senior Researcher : Juan José Lasarte Sagastibelza

more information on Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy

Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer

2016

Senior Researcher : Eva Martín del Valle Research Centre or Institution : Universidad de Salamanca

more information on Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer

The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia

2016

Senior Researcher : Carlos Martínez Alonso Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid

more information on The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia

From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma

2016

Senior Researcher : Enrique María Ocio San Miguel

more information on From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma

Transforming EGFR expressing tumors into immune-rejectable tissues

2016

Senior Researcher : Fernando Pastor Rodríguez

more information on Transforming EGFR expressing tumors into immune-rejectable tissues

Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia

2016

Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia

Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles

2016

Senior Researcher : Fernando Rodríguez Serrano

more information on Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles

The structural bases of tumoral development associated with transcription regulating interactome defects

2014

Senior Researcher : Carlos Fernández Tornero Research Centre or Institution : Centro de Investigaciones Biológicas (CIB) (CSIC)

more information on The structural bases of tumoral development associated with transcription regulating interactome defects

The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase

2014

Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase

Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer

2014

Senior Researcher : Xosé Ramón García Bustelo Research Centre or Institution : Centro de Investigación del Cáncer de Salamanca

more information on Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer

The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer

2014

Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer

Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies

2014

Senior Researcher : Ángel Hernández Hernández Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca.

more information on Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies

Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma

2014

Senior Researcher : José Ángel Martínez-Climent Research Centre or Institution : Centro de Investigación Médica Aplicada de la Universidad de Navarra

more information on Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma

Studies of tumorigenesis in Drosophila: possible clinical implications

2014

Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Studies of tumorigenesis in Drosophila: possible clinical implications

The diagnosis of cancer by means of a metabolic nanosensor platform

2014

Senior Researcher : Ángel Orte Gutiérrez Research Centre or Institution : Facultad de Farmacia. Universidad de Granada

more information on The diagnosis of cancer by means of a metabolic nanosensor platform

The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer

2014

Senior Researcher : Teresa Puig Miquel Research Centre or Institution : Facultad de Medicina. Universidad de Girona

more information on The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer

The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas

2014

Senior Researcher : Rosa Mª Señarís Rodríguez Research Centre or Institution : Departamento de Fisiología. CIMUS. Universidad de Santiago de Compostela

more information on The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas

The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells

2014

Senior Researcher : Aránzazu Tabernero Urbieta Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca.

more information on The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells

Molecular characterisation of the role of mitochondrial dysfunction in tumoral development

2014

Senior Researcher : Ignacio Alejandro Varela Egocheaga Research Centre or Institution : Instituto de Biomedicina y Biotecnología de Cantabria. CSIC-Universidad de Cantabria-SODERCAN.

more information on Molecular characterisation of the role of mitochondrial dysfunction in tumoral development

Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system

2008

Senior Researcher : Miguel Ángel Vidal Caballero Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)

more information on Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system

Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes

2008

Senior Researcher : Manuel Arruebo Gordo Research Centre or Institution : Institute of Nanoscience of Aragón. University of Zaragoza.

more information on Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes

Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype

2006

Senior Researcher : Carlos Pipaón González Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander.

more information on Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype

Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations

2006

Senior Researcher : Francisco Barros Angueira Research Centre or Institution : Hospital Clínico Universitario de Santiago de Compostela. Fundación Pública Galega de Medicina Xenómica.

more information on Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations

Pharmacogenetics in colorectal cancer

2006

Senior Researcher : Luis Andrés López Fernández Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid

more information on Pharmacogenetics in colorectal cancer

Research projects