Research projects
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#Proyectos relacionados con Translational and reverse-translational research in cancer immunotherapy
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Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma
2014
Senior Researcher : José Ángel Martínez-Climent Research Centre or Institution : Centro de Investigación Médica Aplicada de la Universidad de Navarra -
Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)
2020
Senior Researcher : Nuria Malats Riera y Ravid Straussman Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot -
Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination
2020
Senior Researcher : Eva Ortega Paíno Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence
2020
Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular Severo Ochoa. CSIC - UAM -
Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine
2018
Senior Researcher : José Fernández Piqueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis
2018
Senior Researcher : Héctor Peinado Selgas Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid -
Precision medicine approach to target deregulated metabolism in multiple myeloma
2018
Senior Researcher : Francisco Javier Planes Pedreño Research Centre or Institution : TECNUN, Escuela de Ingenieros de la Universidad de Navarramore information on Precision medicine approach to target deregulated metabolism in multiple myeloma
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p38α in control of UV-induced melanoma development and progression
2018
Senior Researcher : Juan Ángel Recio Conde Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelonamore information on p38α in control of UV-induced melanoma development and progression
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Precision medicine: GEF activators of the SOS family as therapeutic targets in Ras-dependent tumors
2018
Senior Researcher : Eugenio Santos de Dios Research Centre or Institution : Instituto de Biología Molecular y Celular del Cáncer. Universidad de Salamanca-CSIC. -
Identification of novel immunotherapeutic targets in lung and melanoma brain metastases
2018
Senior Researcher : Joan Seoane Suárez Research Centre or Institution : Vall d’Hebron Institute of Oncology, VHIO -
Reactive astrocytes as a therapeutic target in brain metastasis
2018
Senior Researcher : Manuel Valiente Cortés Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madridmore information on Reactive astrocytes as a therapeutic target in brain metastasis
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Heterogeneity in melanoma metastasis and resistance to immune checkpoint blockade
2018
Senior Researcher : María S. Soengas y Yardena Samuels Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot -
Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)
2018
Senior Researcher : Alejandro Gómez Roca Research Centre or Institution : Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona. -
A knowledge-based pipeline to increase the diagnosis rate of Rare Diseases using deep sequencing
2016
Senior Researcher : Carmen Ayuso García Research Centre or Institution : Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM). CIBERER. Madrid. -
Dyskeratosis congenita. New models, New molecular keys and New treatments
2016
Senior Researcher : María Luisa Cayuela Fuentes Research Centre or Institution : Hospital Clínico Universitario Virgen de la Arrixaca. Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca. El Palmar, Murcia.more information on Dyskeratosis congenita. New models, New molecular keys and New treatments
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Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
2016
Senior Researcher : Ángel Carracedo Álvarez Research Centre or Institution : Fundación Pública Gallega de Medicina Genómica. Santiago de Compostela. -
Development of new targets for immunotherapy in cancer metastasis
2016
Senior Researcher : José Ignacio Casal Álvarez Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)more information on Development of new targets for immunotherapy in cancer metastasis
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Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
2016
Senior Researcher : Juan José Lasarte Sagastibelza -
Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
2016
Senior Researcher : Eva Martín del Valle Research Centre or Institution : Universidad de Salamanca -
The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
2016
Senior Researcher : Carlos Martínez Alonso Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid -
From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
2016
Senior Researcher : Enrique María Ocio San Miguel -
Transforming EGFR expressing tumors into immune-rejectable tissues
2016
Senior Researcher : Fernando Pastor Rodríguezmore information on Transforming EGFR expressing tumors into immune-rejectable tissues
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Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
2016
Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
2016
Senior Researcher : Fernando Rodríguez Serrano -
The structural bases of tumoral development associated with transcription regulating interactome defects
2014
Senior Researcher : Carlos Fernández Tornero Research Centre or Institution : Centro de Investigaciones Biológicas (CIB) (CSIC) -
The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
2014
Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
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Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer
2014
Senior Researcher : Xosé Ramón García Bustelo Research Centre or Institution : Centro de Investigación del Cáncer de Salamanca -
The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
2014
Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid -
Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies
2014
Senior Researcher : Ángel Hernández Hernández Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca. -
Studies of tumorigenesis in Drosophila: possible clinical implications
2014
Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madridmore information on Studies of tumorigenesis in Drosophila: possible clinical implications
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The diagnosis of cancer by means of a metabolic nanosensor platform
2014
Senior Researcher : Ángel Orte Gutiérrez Research Centre or Institution : Facultad de Farmacia. Universidad de Granadamore information on The diagnosis of cancer by means of a metabolic nanosensor platform
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The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer
2014
Senior Researcher : Teresa Puig Miquel Research Centre or Institution : Facultad de Medicina. Universidad de Girona -
The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas
2014
Senior Researcher : Rosa Mª Señarís Rodríguez Research Centre or Institution : Departamento de Fisiología. CIMUS. Universidad de Santiago de Compostela -
The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells
2014
Senior Researcher : Aránzazu Tabernero Urbieta Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca. -
Molecular characterisation of the role of mitochondrial dysfunction in tumoral development
2014
Senior Researcher : Ignacio Alejandro Varela Egocheaga Research Centre or Institution : Instituto de Biomedicina y Biotecnología de Cantabria. CSIC-Universidad de Cantabria-SODERCAN. -
Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system
2008
Senior Researcher : Miguel Ángel Vidal Caballero Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC) -
Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes
2008
Senior Researcher : Manuel Arruebo Gordo Research Centre or Institution : Institute of Nanoscience of Aragón. University of Zaragoza. -
Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype
2006
Senior Researcher : Carlos Pipaón González Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander. -
Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations
2006
Senior Researcher : Francisco Barros Angueira Research Centre or Institution : Hospital Clínico Universitario de Santiago de Compostela. Fundación Pública Galega de Medicina Xenómica. -
Pharmacogenetics in colorectal cancer
2006
Senior Researcher : Luis Andrés López Fernández Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid
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