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Centros de investigación: Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid

Marcos Malumbres Martínez

Producción científica

Artículos generados en Revistas: 28

Relación de artículos

  • Bueno, M.J., Gómez de Cedrón, M., Laresgoiti, U., Fernández-Piqueras, J., Zubiaga, A. and Malumbres, M. (2010) Multiple E2F-induced microRNAs prevent replicative stress in response to mitogenic signalling. Mol. Cell. Biol. 30, 2983-2995.
  • Fernández-Miranda, G., Pérez de Castro, I., Carmena, M., Aguirre-Portolés, C., Ruchaud, S., Fant, X., Montoya, G., Earnshaw, W.C. and Malumbres, M. (2010) Modulation of Aurora B function by SUMOylation. J. Cell Sci. 123, 2823-2833.
  • Escobar, B.,* de Cárcer, G.,* Fernández-Miranda, G., Cascón, A., Bravo-Cordero, J.J., Montoya, M.C., Robledo, M., Cañamero, M. and Malumbres, M. (2010) Brick1 is an essential regulator of actin cytoskeleton required for embryonic development and cell transformation. Cancer Res. 70, 9349-9359.
  • Manchado, E., Guillamot, M., de Cárcer, G., Eguren, M., Trickey, M., García Higuera, I., Moreno, S., Yamano, H., Cañamero, M. and Malumbres, M. (2010) Targeting mitotic exit leads to tumor regression in vivo: modulation by Cdk1, Mastl, and the PP2A/B55,phosphatase. Cancer Cell 18, 641-654.
  • Manchado, E., Eguren, M. and Malumbres, M. (2010) The anaphase promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions. Biochem. Soc.Trans. 38, 65-71.
  • De Cárcer, G., Escobar, B., Higuero, A., García, L., Ansón, A., Pérez, G., Mollejo, M., Manning, G., Melendez, B., Abad-Rodriguez, J. and Malumbres, M. (2011) Plk5, a Polo-box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression. Mol. Cell. Biol. 31, 1225-1239.
  • Bueno, M.J. and Malumbres, M. (2011) microRNAs and the cell cycle. Biochim. Biophys. Acta 1812, 592-601.
  • Manchado, E. and Malumbres, M. (2011) Targeting aneuploidy for cancer therapy. Cell 144, 465-466.
  • Bueno, M.J., Gómez de Cedrón, M., Gómez-López, G., Pérez de Castro, I., di Lisio, L., Montes, S., Martínez, N., Guerrero, M., Sánchez, R., Santos, J., Pisano, D.G., Piris, M.A., Fernández- Piqueras, J. and Malumbres, M. (2011) Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway. Blood 117, 6255-6266.
  • Eguren, M., Manchado, E. and Malumbres, M. (2011) Non-mitotic functions of the Anaphase-Promoting Complex. Semin. Cell Dev. Biol. 22, 572-578.
  • Chiesa, M.,* Guillamot, M.,* Bueno, M.J. and Malumbres, M. (2011) The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway. Cell Cycle 10, 1607-1617.
  • Fernández-Miranda, G., Trakala, M., Martín, J., Escobar, B., González, A., Ghyselinck, N.B., Ortega, S., Cañamero, M., Pérez de Castro, I. and Malumbres, M. (2011) Genetic disruption of Aurora B uncovers an essential role for Aurora C during early mammalian development. Development 138, 2661-2672.
  • Malumbres, M. (2011) Oncogene-induced mitotic stress: p53 and pRb get Mad too. Cancer Cell 19, 691-692.
  • De Cárcer, G., Manning, G. and Malumbres, M. (2011) From Plk1 to Plk5: functional evolution of Polo-like kinases. Cell Cycle 10, 2255-2262.
  • Malumbres, M. (2011) Physiological relevance of cell cycle kinases. Physiol. Rev. 91, 973-1007.
  • Santamaría, D. and Malumbres, M. (2011) Tumor suppression by Spinophilin. Cell Cycle 10, 2831-2832.
  • Pérez de Castro, I., Aguirre-Portolés, C., Martin, B., Fernández-Miranda, G., Klotzbucher, A., Kubbutat, M.H.G., Megías, D., Arlot-Bonnemains, Y. and Malumbres, M. (2011) A SUMOylation Motif in Aurora-A: Implications in Spindle Dynamics and Oncogenesis. Front. Oncol. - Mol. Cell. Oncol., 1, 50.
  • Guillamot, M., Manchado, E., Chiesa, M., Gómez-López, G., Pisano, D.G., Sacristán, M. and Malumbres, M. (2011) Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription. (Nature) Sci. Reports 1, 189.
  • Malumbres, M. (2012) miRNAs versus oncogenes: the power of social networking. Mol. Syst. Biol. 8, 569. doi: 10.1038/msb.2012.2
  • Aguirre-Portolés, A., Bird, A.W., Hyman, A., Cañamero, M., Pérez de Castro, I. and Malumbres, M. (2012) Tpx2 controls spindle integrity, genome stability and tumor development. Cancer Res. 72, 1518-1528.
  • De Cárcer, G., Pérez de Castro, I. and Malumbres, M. (2012) Inhibiting cell cycle kinases in cancer therapy. Front. Med. Chem. 6, in press.
  • Malumbres, M. (2012) miRNAs and cancer: An epigenetics view. Mol. Aspects Med. Jul 4. doi: 10.1016/j.mam.2012.06.005
  • Malumbres, M. (2012) Cell cycle-based therapies move forward. Cancer Cell 22, 419-420.
  • Pérez de Castro, I. and Malumbres, M. (2013) Mitotic stress and chromosomal instability in cancer: the case for TPX2. Genes & Cancer 3, 721-730.
  • Malumbres, M. (2013) miRNAs and cancer: An epigenetics view. Mol. Aspects Med. Jul 4. doi: 10.1016/j.mam.2012.06.005 [PMID: 22771542]
  • Trakala, M., Fernández-Miranda, G., Pérez de Castro, I., Heeschen, C. and Malumbres, M. (2013) Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21Cip1. Cell Cycle 12, 1030-1041.
  • Doménech, E. and Malumbres, M. (2013) Mitosis-targeting therapies: a troubleshooting guide. Curr. Opin. Pharmacol., in press. doi:pii: S1471-4892(13)00045-3. 10.1016/j.coph.2013.03.011. [Epub ahead of print]
  • Michel, C.I. and Malumbres, M. (2013) microRNA-203: tumor suppression and beyond. microRNA, in press.

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