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Centros de investigación: Instituto Catalán de Oncología. Instituto de Investigación Biomédica de Bellvitge (IDIBELL). Barcelona. Instituto de Investigación Biomédica de Bellvitge (IDIBELL). Barcelona.

Miguel Ángel Genestar Pujana

Producción científica:

  • Artículos generados en Revistas 8
  • Colaboraciones 9
  • Comunicaciones en congresos internacionales 4

Relación de artículos:

  • Serra-Musach J, Aguilar H, Iorio F, Comellas F, Berenguer A, Brunet J, Saez-Rodriguez J, MA Pujana†. (2012). Cancer develops, progresses and responds to therapies through restricted perturbation of the protein-protein interaction network. Integrative Biology 21;4(9):1038-48.
  • Fernández-Rodríguez J, Quiles F, Blanco I, Teulé A, Feliubadaló L, del Valle J, Salinas M, Izquierdo A, Darder E, Schindler D, Capellá G, Brunet J, Lázaro C, MA Pujana †. (2012). Analysis of SLX4/FANCP in non-BRCA1/2-mutated breast cancer families. BMC Cancer 12(1):84.
  • Maxwell CA†, Javier Benítez, Laia Gómez-Baldó, Ana Osorio, Núria Bonifaci, Ricardo Fernández-Ramires, Sylvain V. Costes, Elisabet Guinó, Helen Chen, Gareth J. R. Evans, Pooja Mohan, Isabel Català, Anna Petit, Helena Aguilar, Alberto Villanueva, Alvaro Aytes, Jordi Serra-Musach, Gad Rennert, Flavio Lejbkowicz, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Carla B. Ripamonti, Bernardo Bonanni, Alessandra Viel, Anna Allavena, Loris Bernard, Paolo Radice, Eitan Friedman, Bella Kaufman, Yael Laitman, Maya Dubrovsky, Roni Milgrom, Anna Jakubowska, Cezary Cybulski, Bohdan Gorski, Katarzyna Jaworska, Katarzyna Durda, Grzegorz Sukiennicki, Jan Lubiński, Yin Yao Shugart, Susan M. Domchek, Richard Letrero, Barbara L. Weber, Frans B. L. Hogervorst, Matti A. Rookus, J. Margriet Collee, Peter Devilee, Marjolijn J. Ligtenberg, Rob B. van der Luijt, Cora M. Aalfs, Quinten Waisfisz, Juul Wijnen, Cornelis E. P. van Roozendaal, HEBON, EMBRACE, Douglas F. Easton, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Patricia Harrington, D. Gareth Evans, Fiona Lalloo, Rosalind Eeles, Louise Izatt, Carol Chu, Diana Eccles, Fiona Douglas, Carole Brewer, Heli Nevanlinna, Tuomas Heikkinen, Fergus J. Couch, Noralane M. Lindor, Xianshu Wang, Andrew K. Godwin, Maria A. Caligo, Grazia Lombardi, Niklas Loman, Per Karlsson, Hans Ehrencrona, Anna von Wachenfeldt, SWE-BRCA, Rosa Bjork Barkardottir, Ute Hamann, Muhammad U. Rashid, Adriana Lasa, Trinidad Caldés, Raquel Andrés, Michael Schmitt, Volker Assmann, Kristen Stevens, Kenneth Offit, João Curado, Hagen Tilgner, Roderic Guigó, Gemma Aiza, Joan Brunet, Joan Castellsagué, Griselda Martrat, Ander Urruticoechea, Ignacio Blanco, Laima Tihomirova, David E. Goldgar, Saundra Buys, Esther M. John, Alexander Miron, Melissa Southey, Mary B. Daly, BCFR, Rita K. Schmutzler, Barbara Wappenschmidt, Alfons Meindl, Norbert Arnold, Helmut Deissler, Raymonda Varon-Mateeva, Christian Sutter, Dieter Niederacher, Evgeny Imyamitov, Olga M. Sinilnikova, Dominique Stoppa-Lyonne, Sylvie Mazoyer, Carole Verny-Pierre, Laurent Castera, Antoine de Pauw, Yves-Jean Bignon, Nancy Uhrhammer, Jean-Philippe Peyrat, Philippe Vennin, Sandra Fert Ferrer, Marie-Agnès Collonge-Rame, Isabelle Mortemousque, GEMO Study Collaborators, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing Chen, Sue Healey, kConFab, Mary Helen Barcellos-Hoff, Marc Vidal, Stephen B. Gruber, Conxi Lázaro, Gabriel Capellá, Lesley McGuffog, Katherine L. Nathanson, Antonis C. Antoniou, Georgia Chenevix-Trench, Markus C. Fleisch, Víctor Moreno and MA Pujana†. (2011). Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biology Nov;9(11):e1001199.
  • Bonifaci N, Palafox M, Pellegrini P, Osorio A, Benítez J, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Roversi G, Barile M, Viel A, Mariette F, Bernard L, Radice P, Kaufman B, Laitman Y, Milgrom R, Friedman E, Sáez ME, Climent F, Soler MT, Diez O, Balmaña J, Lasa A, Ramón y Cajal T, Miramar MD, de la Hoya M, Pérez-Segura P, Caldés T, Moreno V, Urruticoechea A, Brunet J, Lázaro C, Blanco I, MA Pujana† and González-Suárez E†. (2011). Evidence for a link between TNFRSF11A and risk of breast cancer. Breast Cancer Research and Treatment 129(3):947-54.
  • Martrat G, Maxwell CA, Tominaga E, Porta-de-la-Riva M, Bonifaci N, Gómez-Baldó L, Bogliolo M, Lázaro C, Blanco I, Brunet J, Aguilar H, Fernández-Rodríguez J, Seal S, Renwick A, Rahman N, Kühl J, Neveling K, Schindler D, Ramírez MJ, Castellà M, Hernández G; EMBRACE, Easton DF, Peock S, Cook M, Oliver CT, Frost D, Platte R, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Davidson R, Ong KR, Cook J, Douglas F, Hodgson S, Brewer C, Morrison PJ, Porteous M, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Roversi G, Barile M, Viel A, Pasini B, Ottini L, Putignano AL, Savarese A, Bernard L, Radice P, Healey S, Spurdle A, Chen X, Beesley J; kConFab, Rookus MA, Verhoef S, Tilanus-Linthorst MA, Vreeswijk MP, Asperen CJ, Bodmer D, Ausems MG, van Os TA, Blok MJ, Meijers-Heijboer HE, Hogervorst FB; HEBON, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB; BCFR; SWE-BRCA, Harbst K, Borg A, Rantala J, Barbany-Bustinza G, Ehrencrona H, Stenmark-Askmalm M, Kaufman B, Laitman Y, Milgrom R, Friedman E, Domchek SM, Nathanson KL, Rebbeck TR, Johannsson OT, Couch FJ, Wang X, Fredericksen Z, Cuadras D, Moreno V, Pientka FK, Depping R, Caldés T, Osorio A, Benítez J, Bueren J, Heikkinen T, Nevanlinna H, Hamann U, Torres D, Caligo MA, Godwin AK, Imyanitov EN, Janavicius R; GEMO Study Collaborators, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, Verny-Pierre C, Castera L, de Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Ferrer SF, Collonge-Rame MA, Mortemousque I, McGuffog L, Chenevix-Trench G, Pereira-Smith OM, Antoniou AC, Cerón J†, Tominaga K†, Surrallés J† and MA Pujana†. (2011). Exploring the link between MORF4L1 and risk of breast cancer. Breast Cancer Research 13(2):R40.
  • N Bonifaci, B Górski, B Masojć, D Wokołorczyk, A Jakubowska, T Dębniak, A Berenguer, J Serra Musach, J Dopazo, SA Narod, J Lubinski, C Lázaro, C Cybulski† and MA Pujana†. (2010). Cancer-driving kinases may commonly influence risk of breast cancer. PLoS One e14078.
  • H Aguilar, X Solé, N Bonifaci, J Serra Musach, A Islam, N López-Bigas, M Méndez-Pertuz, RL Beijersbergen, C Lázaro, A Urruticoechea† and MA Pujana†. (2010). Biological reprogramming in acquired resistance to endocrine treatment of breast cancer. Oncogene 29(45):6071-83.
  • L Gómez-Baldó, S Schmidt, CA Maxwell, N Bonifaci, T Gabaldón, PO Vidalain, W Senapedis, A Kletke, M Rosing, A Barnekow, R Rottapel, G Capellá, M Vidal, A Astrinidis†, RP Piekorz† and MA Pujana†. (2010). TACC3-TSC2 maintain nuclear envelope structure and control cell division. Cell Cycle 9(6).

Relación de colaboraciones:

  • Pellegrini P, Cordero A, Gallego MI, Dougall WC, Muñoz P, MA Pujana, Gonzalez-Suarez E. (2013). Constitutive activation of RANK disrupts mammary cell fate leading to tumorigenesis. Stem Cells 14 Jun.
  • Couch FJ, Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker K, Fredericksen Z, Barrowdale D, Dennis J, Gaudet MM, Ed Dicks, Matthew Kosel , Sue Healey, Olga Sinilnikova, Penny Soucy, Adam Lee, François Bacot, Daniel Vincent, Frans B.L. Hogervorst, Susan Peock, Dominique Stoppa-Lyonnet, Anna Jakubowska, KConFab Investigators, Paolo Radice, Rita Katharina Schmutzler, SWE-BRCA, Susan M. Domchek, Marion Piedmonte, Christian F Singer, Eitan Friedman, Mads Thomassen, OCGN, Thomas v. O. Hansen, Susan L. Neuhausen, Csilla I. Szabo, Ignacio Blanco, Mark H. Greene, Beth Y. Karlan, Judy Garber, Catherine M Phelan, Jeffrey N. Weitzel, Marco Montagna, Edith Olah, Irene L. Andrulis, Andrew K. Godwin, Drakoulis Yannoukakos, David E Goldgar, Trinidad Caldes, Heli Nevanlinna, Ana Osorio, Mary Beth Terry, Mary B Daly, Elizabeth J van Rensburg, Ute Hamann, Susan J Ramus, Amanda Ewart Toland, Maria A. Caligo, Olufunmilayo I Olopade, Nadine Tung, Kathleen Claes, Mary S. Beattie, Melissa Southey, Evgeny N. Imyanitov, Marc Tischkowitz, Ramunas Janavicius, Esther M John, Ava Kwong, Orland Diez, Rosa B Barkardottir, Banu K Arun, Gad Rennert, Soo-Hwang Teo, Patricia A. Ganz, Ian Campbell, Annemarie H. van der Hout, Carolien H.M. van Deurzen, Caroline Seynaeve, Encarna B. Gómez Garcia, Flora E. van Leeuwen, Hanne E.J. Meijers-Heijboer, Quinten Waisfisz, Margreet G.E.M. Ausems, Marinus J. Blok, Marjolijn J.L. Ligtenberg, Matti A. Rookus, Peter Devilee, Senno Verhoef, Theo A.M. van Os, Juul T. Wijnen, HEBON, Alan Donaldson, Carole Brewer, D. Gareth Evans, Debra Frost, Diana Eccles, Elena Fineberg, Fiona Douglas, Helen Gregory, Huw Dorkins, Jackie Cook, Julian Adlard, Louise Izatt, Lucy E. Side, Mark T. Rogers, Patrick J. Morrison, Radka Platte, Rosalind A. Eeles, Shirley Hodgson, Steve D. Ellis, Alex Murray, Emma McCann, Jacqueline Eason, Catherine Houghton, EMBRACE, Alain Calender, Agnès Hardouin , Pascaline Berthet , Capucine Delnatte, Catherine Nogues, Christine Lasset, Claude Houdayer, Dominique Leroux, Etienne Rouleau, Fabienne Prieur, Francesca Damiola, Hagay Sobol, Isabelle Coupier, Laurence Venat-Bouvet, Laurent Castera, Marion Gauthier-Villars, Pascal Pujol, Sylvie Mazoyer, Yves-Jean Bignon, GEMO Study Collaborators, Elżbieta Złowocka-Perłowska, Jacek Gronwald, Jan Lubinski, Katarzyna Durda , Katarzyna Jaworska, Tomasz Huzarski, Amanda B. Spurdle, Alessandra Viel, Bernard Peissel, Bernardo Bonanni, Giulia Melloni, Laura Ottini, Laura Papi, Liliana Varesco, Maria Grazia Tibiletti, Paolo Peterlongo, Sara Volorio, Siranoush Manoukian, Valeria Pensotti, Arnold, Norbert, Christoph Engel, Helmut Deissler, Dorothea Gadzicki, Andrea Gehrig, Karin Kast, Kerstin Rhiem, Alfons Meindl, Dieter Niederacher, Nina Ditsch, Hansjoerg Plendl, Sabine Preisler-Adams, , Stefanie Engert, Doris Steinemann, Christian Sutter, Raymonda Varon-Mateeva, Barbara Wappenschmidt, Bernhard H.Weber, Brita Arver, Marie Stenmark-Askmalm, Niklas Loman, Richard Rosenquist, Zakaria Einbeigi, Katherine L. Nathanson, Timothy R. Rebbeck, Stephanie V. Blank, David E. Cohn, Gustavo C. Rodriguez, Laurie Small, Michael Friedlander, Victoria L. Bae-Jump, Anneliese Fink-Retter, Christine Rappaport, Daphne Geschwantler Kaulich, Georg Pfeiler, Muy-Kheng Tea, Noralane Lindor, Bella Kaufman, Shani Shimon Paluch, Yael Laitman , Anne-Bine Skytte, Anne-Marie Gerdes, Inge Sokilde Pedersen, Sanne Traasdahl Moeller, Torben A. Kruse, Uffe Birk Jensen, Joseph Vijai, Kara Sarrel, Mark Robson ,Noah Kauff ,Anna Marie Mulligan, Gord Glendon, Hilmi Ozcelik, Bent Ejlertsen, Finn C. Nielsen, Lars Jønson, Mette K. Andersen, Yuan Chun Ding, Linda Steele, Lenka Foretova, Alex Teulé, Conxi Lazaro, Joan Brunet, MA Pujana, Phuong L. Mai, Jennifer T Loud, Christine Walsh, Jenny Lester, Sandra Orsulic, Steven A Narod, Josef Herzog, Sharon R. Sand, Silvia Tognazzo, Simona Agata, Tibor Vaszko, JoEllen Weaver, Alexandra V Stavropoulou, Saundra S Buys, Atocha Romero, Miguel de la Hoya, Kristiina Aittomäki, Taru A. Muranen, Mercedes Duran, Wendy K. Chung, Adriana Lasa , Cecilia M Dorfling, Alex Miron, BCFR, Javier Benitez, Leigha Senter, Dezheng Huo, Salina B. Chan, Anna P. Sokolenko, Jocelyne Chiquette, Laima Tihomirova, Tara Friebel, Bjarni A Agnarsson ,Karen H Lu, Flavio Lejbkowicz, Paul James, Per Hall, Alison Dunning, Daniel Tessier, Julie Cunningham, Susan Slager, Chen Wang, Steven Hart, Jacques Simard, Kristen Stevens, Pastinen T, Pankratz VS, Offit K, Easton DF, Chenevix-Trench G, Antoniou AC. (2013). Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genetics 9(3):e1003212.
  • Quiles F, Fernández-Rodríguez J, Mosca R, Feliubadaló L, Tornero E, Brunet J, Blanco I, Capellá G, MA Pujana, Aloy P, Monteiro A, Lázaro C. (2013). Functional and structural analysis of C-terminal BRCA1 missense variants. PLoS One 8(4):e61302.
  • Berdasco M, Melguizo C, Prados J, Gómez A, Alaminos M, MA Pujana, Lopez M, Setien F, Ortiz R, Zafra I, Aranega A, Esteller M. (2012). DNA methylation plasticity of human adipose-derived stem cells in lineage commitment. American Journal of Pathology 181(6):2079-93.
  • Vidal A, Munoz C, Guillen MJ, Moreto J, Sara P, Martinez-Iniesta M, Figueras A, Padulles L, Garcia-Rodriguez FJ, Berdiel-Acer M, MA Pujana, Salazar R, Gil-Martin M, Marti L, Ponce J, Mollevi DG, Capella G, Condom E, Vinals F, Huertas D, Cuevas C, Esteller M, Aviles P, Villanueva A. (2012). Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer. Clinical Cancer Research 18(19):5399-411.
  • Holger H, Ning L, Humberto JF,Moran S, Pisano DG, Gomez A, Diez J, Sanchez-Mut JV, Setien F, Carmona JF, Puca AA, Sayols S, MA Pujana, Serra-Musach J, Iglesias-Plata I, Formiga F, Fernandez AF, Fraga MF, Heath SC, Valencia A, Gut IG, Wang J, Esteller M. (2012). The distinct DNA methylomes of newborns and centenarians. Proceedings of the National Academy of Sciences USA 109(26):10522-7.
  • Sanz-Pamplona R, Berenguer A, Sole X, Cordero D, Crous-Bou M, Serra-Musach J, Guinó E, MA Pujana, Moreno V. (2012). Tools for protein-protein interaction network analysis in cancer research. Clinical Translational Oncology 14(1):3-14.
  • Sanz-Pamplona R, Cordero D, Berenguer A, Lejbkowicz F, Rennert HS, Salazar R, Biondo S, Sanjuan X, MA Pujana, Rozek L, Giordano TJ, Ben-Izhak O, Cohen HI, Trougouboff P, Bejhar J, Sova Y, Rennert G, Gruber SB and Moreno V. (2011). Gene expression differences between colon and rectum tumors. Clinical Cancer Research 17(23):7303-12.
  • Sandoval J, Heyn HA, Moran S, Serra-Musach J, MA Pujana, Bibikova M and Esteller M. (2011). Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics. 6(6):692-702.

Relación de comunicaciones en congresos internacionales:

  • Tipo de participación: póster "Patient derived tumor xenografts as an approach to the study of triple negative breast cancer chemoresistance"
    Congreso: European Association for Cancer Research
    Lugar de celebración: Cambridge, UK. Año: 2010
  • Tipo de participación: póster "Towards a complete understanding of the FA/BRCA signaling pathway"
    Congreso: IDIBELL Cancer Conference - EMBO Workshop on Tumor Suppressors
    Lugar de celebración: L'Hospitalet del Llobregat, Barcelona. Año: 2010
  • Tipo de participación: póster "MRG15, a novel partner of PALB2, and risk of breast cancer"
    Congreso: 23rd Annual Scientific Symposium of Fanconi Anemia
    Lugar de celebración: Barcelona. Año: 2011
  • Tipo de participación: póster "A transcription-based mechanism of resistance to allosteric mTOR inhibition mediates lung metastatic potential of breast cancer"
    Congreso: IDIBELL Cancer Conference on Personalized Medicine
    Lugar de celebración: L'Hospitalet del Llobregat, Barcelona. Año: 2012

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