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Life and Matter Sciences Research

XVIII National Competition

From march 2, 2017 until march 2, 2020.

Rare diseases

  Investigation project Senior Researcher Research Centre
Ángeles Almeida Parra The function of the E3 ubiquitin ligase APC/C-Cdh1 in Fragile X Syndrome. Possible therapeutic application Ángeles Almeida Parra Instituto de Investigación Biomédica de Salamanca (IBSAL)
Carmen Ayuso García A knowledge-based pipeline to increase the diagnosis rate of Rare Diseases using deep sequencing Carmen Ayuso García  Instituto de Investigación Sanitaria Fundación Jiménez Díaz
(IIS-FJD, UAM). CIBERER. Madrid
Paola Bovolenta Nicolao Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases Paola Bovolenta Nicolao  Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid
Dyskeratosis congenita. New models, New molecular keys and New treatments María Luisa Cayuela Fuentes Instituto de Investigación Biosanitaria-IMIB.
Instituto Murciano de Investigaciones Biosanitarias-Arrixaca.
César Cobaleda Hernández Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-) César Cobaleda Hernández  Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid.
Visualisation of neuronal polysomal architecture and its alterations in Huntington's Disease José Jesús Fernández Rodríguez  Centro Nacional de Biotecnología. CSIC. Madrid
Modeling of familial cerebral cavernous malformation through cellular reprogramming Miguel Ángel Fidalgo Pérez Centro de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS). Universidad de Santiago de Compostela
Phosphodiesterase inhibitors as Friedreich's ataxia treatment Pilar González Cabo  Centro de Investigación Biomédica en Red (CIBER de Enfermedades Raras). Facultad de Medicina y Odontología. Universidad de Valencia
Activation of innate immunity in dysferlin-deficient cells: new therapeutic targets Noemí de Luna Salvà  Laboratorio de Enfermedades Neuromusculares. 
Hospital de la Santa Creu i Sant Pau. CIBER (Centro de Investigación Biomédica en Red). Barcelona
The connection between rare diseases and common diseases: dysfunction of copper homeostasis and mitochondria as a model (NeuroCopper) Francesc Palau Martínez Instituto de Investigación Sanitaria Sant Joan de Déu y Hospital Sant Joan de Déu. Barcelona
María del Carmen Sánchez Fernández Towards the improvement of diagnosis and treatment in Congenital Dyserythropoyetic Anaemias María del Carmen Sánchez Fernández  Universidad Internacional de Cataluña UIC
Pascual Felipe Sanz Bigorra Astrocytes: new anti-epileptic targets in Lafora disease Pascual Felipe Sanz Bigorra Instituto de Biomedicina de Valencia. CSIC y Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER)
Jorgina Satrústegui Gil-Delgado AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies Jorgina Satrústegui Gil-Delgado  Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid

Inmunotherapy and cancer

  Investigation project Senior Researcher Research Centre
Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC Ángel Carracedo Álvarez  Fundación Pública Galega de Medicina Xenómica. Santiago de Compostela
José Ignacio Casal Álvarez Development of new targets for immunotherapy in cancer metastasis José Ignacio Casal Álvarez  Centro de Investigaciones Biológicas Margarita Salas. CSIC. Madrid
Juan José Lasarte Sagastibelza Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy Juan José Lasarte Sagastibelza Centro de Investigación Médica Aplicada, CIMA. Fundación para la Investigación Médica Aplicada. Pamplona
Eva Martín del Valle Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer Eva Martín del Valle Universidad de Salamanca
Carlos Martínez Alonso The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia Carlos Martínez Alonso Centro Nacional de Biotecnología. CSIC. Madrid
Enrique María Ocio San Miguel From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma Enrique María Ocio San Miguel Hospital Universitario de Salamanca. Instituto de Investigación Biomédica de Salamanca (IBSAL)
Fernando Pastor Rodríguez Transforming EGFR expressing tumors into immune-rejectable tissues Fernando Pastor Rodríguez Fundación para la Investigación Médica Aplicada. Pamplona
Hisse Martien van Santen Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia Hisse Martien van Santen Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid

Cell therapy in neurodegenerative diseases

  Investigation project Senior Researcher Research Centre
Carlos Vicario Abejón Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. Rescue of the phenotype and cell transplantation Carlos Vicario Abejón Instituto Cajal. CSIC. Madrid

Interactome: pathological implications

  Investigation project Senior Researcher Research Centre
Inés María Antón Gutiérrez WIP differential interactome during its oncogenic or tumor suppressor activity Inés María Antón Gutiérrez Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas-Centro Nacional de Biotecnología. CIBERNED/CNB-CSIC. Madrid 
María Jesús Bullido Gómez-Heras Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons María Jesús Bullido Gómez-Heras Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid
Interactions of the protein N-acetylglucosamine kinase with different elements of gene regulation in Yarrowia lipolytica Carlos Gancedo Rodríguez Instituto de Investigaciones Biomédicas "Alberto Sols". CSIC-UAM. Madrid
Identification of the nucleotide cellular sensor and its interactome Marçal Pastor Anglada CIBEREHD-Universitat de Barcelona
Yolanda Revilla Novella Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators Yolanda Revilla Novella Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid

Exosomes: intercelular communication as a therapeutic weapon

  Investigation project Senior Researcher Research Centre
Roberto Álvarez Lafuente Study of EBV, HHV-6A AND HHV-6B MICRO-RNAs in plasma isolated exosomes of patients with multiple sclerosis: correlation with activity and progression of disease Roberto Álvarez Lafuente  Hospital Universitario Clínico San Carlos. Instituto de Investigación Sanitaria San Carlos (IdISSC). Madrid
Alberto Dávalos Herrera Modulation of exosomes transporting miRNAs and lncRNAs for intercellular communication as therapeutic tools in dyslipidemia treatment Alberto Dávalos Herrera  Fundación IMDEA Alimentación. Madrid.
Vicente Emilio Larraga Rodríguez de Vera Characterization of infection biomarkers and possible drug targets present into exosome vesicles generated during in vitro and in vivo infection by Leishmania infantum Vicente Emilio Larraga Rodríguez de Vera Centro de Investigaciones Biológicas Margarita Salas. CSIC. Madrid
Fernando Rodríguez Serrano Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles Fernando Rodríguez Serrano  Facultad de Medicina. Centro de Investigación Biomédica. Universidad de Granada
Antonio Zorzano Olarte Investigating the molecular mechanisms of exosome production under cellular stress Antonio Zorzano Olarte Instituto de Investigación Biomédica (IRB) Barcelona

Tissue reprogramming and organoids

  Investigation project Senior Researcher Research Centre
Antonio Baonza Cuenca Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming Antonio Baonza Cuenca Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid
Role of Purinergic signaling in human cortical development. A cerebral organoid-based approach María Teresa Miras-Portugal  Departamento de Bioquímica y Biología Molecular, Facultad de Veterinaria, Universidad Complutense de Madrid. Madrid

Food security and biotechnology

  Investigation project Senior Researcher Research Centre
Pablo José Fernández-Marcos New food-derived bioactive products against obesity and diabetes Pablo José Fernández-Marcos  Fundación IMDEA Alimentación. Madrid
Ana Iglesias Juez Advanced photo systems with biocidal properties for coatings development with application in food and hospital safety Ana Iglesias Juez Instituto de Catálisis y Petroleoquímica. CSIC. Madrid.
Fernando Martín Belmonte Using animal models for testing interventions targeting malnutrition and stunting in children Fernando Martín Belmonte Centro de Biología Molecular Severo Ochoa. CSIC-UAM. Madrid
Jorge Pérez Juste Development of Lab-on-a-chip nanostructured sensors for the detection of pathogens and food-borne chemical agents based on Surface-Enhanced Raman Spectroscopy (SERS) Jorge Pérez Juste  Centro de Investigaciones Biomédicas CINBIO. Universidade de Vigo.
Amparo Querol Simón Novel insights, tools and measures to mitigate emerging risk by yeasts in the food chain Amparo Querol Simón  Instituto de Agroquímica y Tecnología de Alimentos. CSIC. Paterna, Valencia.
Miguel Ángel Sogorb Sánchez Towards a new paradigm in the identification of hazards and evaluation of the safety and risk of neurotoxicity associated to the exposure to nanomaterials with biotechnological applications Miguel Ángel Sogorb Sánchez  Instituto de Bioingeniería. Universidad Miguel Hernández de Elche

Renewable energy: materials and processes

  Investigation project Senior Researcher Research Centre
Álvaro Campos Celador Latent heat thermal energy storage by urea-based eutectic mixtures Álvaro Campos Celador Universidad del País Vasco (UPV-EHU)
Mª Dolores Esquivel Merino Heterogeneous biomimetic catalysts based on functionalized organic-inorganic hybrid networks to produce hydrogen Mª Dolores Esquivel Merino  Instituto de Química Fina y Nanoquímica. Universidad de Córdoba
María González Béjar Sunlight on nanocatalysts to lower global energy use, emissions and pollution María González Béjar Instituto de Ciencia Molecular. Universitat de València
Manuel Moliner Marín Efficient materials for the capture and selective transformation of CO2 towards value-added chemicals Manuel Moliner Marín Instituto de Tecnología Química. CSIC-UPV. Valencia
Sergio Navalón Oltra Metal-organic frameworks as heterogeneous photocatalysts for CO2 reduction and H2 generation using H2O Sergio Navalón Oltra Departamento de Química. Universitat Politècnica de València
Miguel A. Sierra Rodríguez Development of Mimics of Hidrogenases Modulated by Transition Metal Complexes to Produce Hydrogen in the Absence of Molecular Reducing Agents Miguel A. Sierra Rodríguez  Facultad de Química. Universidad Complutense de Madrid. Madrid
Carlos Vázquez Vázquez Photoproduction of hydrogen with atomic quantum clusters using visible light Carlos Vázquez Vázquez  Instituto de Investigaciones Tecnológicas. Laboratorio NANOMAG. Santiago de Compostela (A Coruña)

Graphene, foundations and applications

  Investigation project Senior Researcher Research Centre
Lisardo Boscá Gomar Graphene: macrophage biomaterials: functional characterization for the use in cardiovascular pathologies Lisardo Boscá Gomar  Instituto de Investigaciones Biomédicas Alberto Sols. CSIC-UAM. Madrid
Iván Brihuega Álvarez Controlling the magnetism and electronic transport of graphene samples at the atomic scale Iván Brihuega Álvarez Universidad Autónoma de Madrid
José Antonio Garrido Ariza Graphene-based flexible neural interfaces for the peripheral nervous system José Antonio Garrido Ariza Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona

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