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Brain plasticity: Aging and neuropsychiatric disorders

Life and Matter Sciences International Symposium May 13-14, 2008 Madrid

General information

Place: Salón de Actos Fundación Ramón Areces Vitruvio, 5 28006 Madrid

Free assistance

Organized by:

Fundación Ramón Areces

Coordinator/s:

Francisco MoraUniversidad Complutense. Madrid. Spain.

Luigi AgnatiUniversità di Modena. Italy.

Kjell FuxeKarolinska Institutet. Estocolmo. Sweden.

Description
Programme

The brain is a plastic organ which changes constantly as a result of its interaction with the environment, being this physical, emotional or social. Recent research has shown that the expression of genes-environment interaction modulates the brain in processes such as aging, psychiatric diseases and drug addiction.In fact some studies are showing that certain styles of life and the social environments do influence positively these processes.

Results from ongoing research in these topics will be presented and discussed in this symposium. Specifically the topics will range from the influence of an enriched environment on the effects of stress in aged animals and also the role of brain neurotrophic factors on aging up to the plastic mechanisms that are the neural substrates of drug addiction. Also those new concepts about receptor mosaics and the receptor-receptor interactions in the normal brain and psychiatric and neurodegenerative disorders will be discussed.

Report

Tuesday, 13

09:15

Opening

José María Segovia de Arana
Consejo Científico.
Fundación Ramón Areces.
Spain.

09:45

Introduction

Francisco Mora
Symposium Coordinator.

FIRST SESSION

Chairman:

David C.S. Roberts
Wake Forest University Health Sciences. Winston-Salem. USA.

10:15

On the role of brain receptor mosaics and their receptor-receptor interactions in neuropsychiatric disorders

Kjell Fuxe
Symposium Coordinator.

11:00

Break

11:30

Prefrontal cortex-nucleus accumbens interactions and environmental enrichment: Role of dopamine, acetylcholine and glutamate

Alberto del Arco
Universidad Complutense.
Madrid. Spain.

12:15

Stress, personality and vulnerability to psychopathology: Neurobiological correlates

Carmen Sandi
Brain Mind Institute. Lausanne. Switzerland.

13:00

General discussion

13:30

Break

SECOND SESSION

16:00

The role of protein mosaics in neurodegeneration

Luigi Agnati
Symposium Coordinator.

16:45

The neurogenic niche in the carotid body and its applicability to aniparkinsonian cell therapy

José López-Barneo
Universidad de Sevilla.
Spain.

17:30

Break

17:45

Receptor heteromers in neurodegenerative diseases and in neural plasticity

Rafael Franco
Universidad de Barcelona.
Spain.

18:30

General discussion

Wednesday, 14

FIRST SESSION

Chairman:

Luigi Agnati
Symposium Coordinator.

09:30

Neurotrophic systems promoting neurogenesis in aged rat brain

Natale Belluardo
Università di Palermo.
Italy.

10:15

Aging and Alzheimer's neuropathology in Down Syndrome

Jesús Flórez
Universidad de Cantabria.
Santander. Spain.

11:00

Break

11:30

Environmental enrichment, stress and aging of the brain

Gregorio Segovia
Universidad Complutense.
Madrid. Spain.

12:15

General discussion

13:00

Break

SECOND SESSION

Chairman:

Kjell Fuxe
Symposium Coordinator.

16:00

Plasticity in the neural mechanisms underlying the development of compulsive drug seeking and addiction

Barry Everitt
University of Cambridge.
UK.

16:45

Brain plasticity revealed through studies of drug reinforcement and addiction

David C.S. Roberts

17:30

Break

17:45

Short and long-term consequences of prenatal exposure to cannabinoid agonist WIN55,212-2 on glutamatergic transmission and cognitive functions in rat offspring

Sergio Tanganelli
Università di Ferrara.
Italy.

18:30

General discussion

19:00

Concluding Remarks

Kjell Fuxe
Symposium Coordinator.

Luigi Agnati
Symposium Coordinator.

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