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Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)
2020
Senior Researcher : Nuria Malats Riera y Ravid Straussman
Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot
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on Tumor microbiome and immune profiles as predictors of treatment response in high-risk non-muscle invasive bladder cancer (MIT-BC Study)
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Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination
2020
Senior Researcher : Eva Ortega Paíno
Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid
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on Spanish National Brain Metastasis Network (RENACER): Implementation, Development and Coordination
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Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence
2020
Senior Researcher : Petronila Penela Márquez
Research Centre or Institution : Centro de Biología Molecular Severo Ochoa. CSIC - UAM
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on Exploring post-translational regulation of angiogenic and inflammatory-related processes during colorectal cancer progession and differential recurrence
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Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine
2018
Senior Researcher : José Fernández Piqueras
Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid
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on Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine
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Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis
2018
Senior Researcher : Héctor Peinado Selgas
Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid
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on Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis
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Precision medicine approach to target deregulated metabolism in multiple myeloma
2018
Senior Researcher : Francisco Javier Planes Pedreño
Research Centre or Institution : TECNUN, Escuela de Ingenieros de la Universidad de Navarra
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on Precision medicine approach to target deregulated metabolism in multiple myeloma
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p38α in control of UV-induced melanoma development and progression
2018
Senior Researcher : Juan Ángel Recio Conde
Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelona
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on p38α in control of UV-induced melanoma development and progression
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Precision medicine: GEF activators of the SOS family as therapeutic targets in Ras-dependent tumors
2018
Senior Researcher : Eugenio Santos de Dios
Research Centre or Institution : Instituto de Biología Molecular y Celular del Cáncer. Universidad de Salamanca-CSIC.
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on Precision medicine: GEF activators of the SOS family as therapeutic targets in Ras-dependent tumors
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Identification of novel immunotherapeutic targets in lung and melanoma brain metastases
2018
Senior Researcher : Joan Seoane Suárez
Research Centre or Institution : Vall d’Hebron Institute of Oncology, VHIO
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on Identification of novel immunotherapeutic targets in lung and melanoma brain metastases
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Reactive astrocytes as a therapeutic target in brain metastasis
2018
Senior Researcher : Manuel Valiente Cortés
Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid
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on Reactive astrocytes as a therapeutic target in brain metastasis
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Heterogeneity in melanoma metastasis and resistance to immune checkpoint blockade
2018
Senior Researcher : María S. Soengas y Yardena Samuels
Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas. Madrid y el Weizman Institute of Science. Rehovot
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on Heterogeneity in melanoma metastasis and resistance to immune checkpoint blockade
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Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)
2018
Senior Researcher : Alejandro Gómez Roca
Research Centre or Institution : Instituto Catalán de Nanociencia y Nanotecnología. Bellaterra, Barcelona.
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on Magnetoplasmonic control (actuation and monitoring) of drug release using Fe/Au semi‐shells on biodegradable nanoparticles (MAGPLADRUG)
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Dyskeratosis congenita. New models, New molecular keys and New treatments
2016
Senior Researcher : María Luisa Cayuela Fuentes
Research Centre or Institution : Hospital Clínico Universitario Virgen de la Arrixaca. Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca. El Palmar, Murcia.
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on Dyskeratosis congenita. New models, New molecular keys and New treatments
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Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
2016
Senior Researcher : Ángel Carracedo Álvarez
Research Centre or Institution : Fundación Pública Gallega de Medicina Genómica. Santiago de Compostela.
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on Genomic and transcriptomic study of circulating tumor lymphocytes for the development of biomarkers associated with the response to treatment with inhibitors of the PD-L1 / PD1 pathway in patients with NSCLC
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Development of new targets for immunotherapy in cancer metastasis
2016
Senior Researcher : José Ignacio Casal Álvarez
Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)
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on Development of new targets for immunotherapy in cancer metastasis
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Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
2016
Senior Researcher : Juan José Lasarte Sagastibelza
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on Gene editing of key transcription factors to improve the antitumor efficacy of Adoptive T cell Therapy
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Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
2016
Senior Researcher : Eva Martín del Valle
Research Centre or Institution : Universidad de Salamanca
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on Development and validation of an aerosol with intelligent nanoparticles in order to treat lung cancer
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The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
2016
Senior Researcher : Carlos Martínez Alonso
Research Centre or Institution : Centro Nacional de Biotecnología (CNB). CSIC. Madrid
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on The Role of Dido in Lymphoid and Myeloid Development and Its Implications in Neoplasia
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From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
2016
Senior Researcher : Enrique María Ocio San Miguel
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on From preclinical models to the patient: a holistic investigation of immunotherapies in multiple myeloma
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Transforming EGFR expressing tumors into immune-rejectable tissues
2016
Senior Researcher : Fernando Pastor Rodríguez
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on Transforming EGFR expressing tumors into immune-rejectable tissues
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Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
2016
Senior Researcher : Hisse Martien van Santen
Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid
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on Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia
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Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
2016
Senior Researcher : Fernando Rodríguez Serrano
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on Applicability of exosomes as predictors of response to treatment and prognosis in breast cancer: cellular modifications induced by the interaction of exovesicles
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The structural bases of tumoral development associated with transcription regulating interactome defects
2014
Senior Researcher : Carlos Fernández Tornero
Research Centre or Institution : Centro de Investigaciones Biológicas (CIB) (CSIC)
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on The structural bases of tumoral development associated with transcription regulating interactome defects
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The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
2014
Senior Researcher : José Manuel Cuezva Marcos
Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid
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on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase
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Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer
2014
Senior Researcher : Xosé Ramón García Bustelo
Research Centre or Institution : Centro de Investigación del Cáncer de Salamanca
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on Pharmaco-mimetic analysis of the therapeutic value of Vav-dependent metabolic routes in breast cancer
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The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
2014
Senior Researcher : César Jesús de Haro Castella
Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid
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on The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer
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Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies
2014
Senior Researcher : Ángel Hernández Hernández
Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca.
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on Oxidise NADPH and the regulation of intermediate leukemic cell metabolism: the search for new therapeutic strategies
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Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma
2014
Senior Researcher : José Ángel Martínez-Climent
Research Centre or Institution : Centro de Investigación Médica Aplicada de la Universidad de Navarra
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on Inhibition of the protein that regulates SLC4A2 cell ion metabolism as a new therapy in leukaemia, lymphoma and myeloma
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Studies of tumorigenesis in Drosophila: possible clinical implications
2014
Senior Researcher : Ginés Morata Pérez
Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid
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on Studies of tumorigenesis in Drosophila: possible clinical implications
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The diagnosis of cancer by means of a metabolic nanosensor platform
2014
Senior Researcher : Ángel Orte Gutiérrez
Research Centre or Institution : Facultad de Farmacia. Universidad de Granada
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on The diagnosis of cancer by means of a metabolic nanosensor platform
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The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer
2014
Senior Researcher : Teresa Puig Miquel
Research Centre or Institution : Facultad de Medicina. Universidad de Girona
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on The inhibition of fatty acid syntase lipogenic enzyme (FASN) as a new therapeutic strategy for the treatment of triple negative breast cancer
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The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas
2014
Senior Researcher : Rosa Mª Señarís Rodríguez
Research Centre or Institution : Departamento de Fisiología. CIMUS. Universidad de Santiago de Compostela
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on The AMPK enzyme, a nexus joined metabolism and cancer. A new therapeutic strategy in cerebral glyoblastomas
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The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells
2014
Senior Researcher : Aránzazu Tabernero Urbieta
Research Centre or Institution : Instituto de Neurociencias de Castilla y León. Universidad de Salamanca.
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on The effect of antitumour penetrating peptides based on connexin-43 in the selective metabolic reprogramming of human glyoma stem cells
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Molecular characterisation of the role of mitochondrial dysfunction in tumoral development
2014
Senior Researcher : Ignacio Alejandro Varela Egocheaga
Research Centre or Institution : Instituto de Biomedicina y Biotecnología de Cantabria. CSIC-Universidad de Cantabria-SODERCAN.
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on Molecular characterisation of the role of mitochondrial dysfunction in tumoral development
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Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system
2008
Senior Researcher : Miguel Ángel Vidal Caballero
Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)
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on Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system
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Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes
2008
Senior Researcher : Manuel Arruebo Gordo
Research Centre or Institution : Institute of Nanoscience of Aragón. University of Zaragoza.
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on Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes
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Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype
2006
Senior Researcher : Carlos Pipaón González
Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander.
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on Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype
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Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations
2006
Senior Researcher : Francisco Barros Angueira
Research Centre or Institution : Hospital Clínico Universitario de Santiago de Compostela. Fundación Pública Galega de Medicina Xenómica.
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on Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations
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Pharmacogenetics in colorectal cancer
2006
Senior Researcher : Luis Andrés López Fernández
Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid
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on Pharmacogenetics in colorectal cancer