Listado de proyectos - Fundación Ramón Areces

Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)

2016

Investigador Principal: César Cobaleda Hernández Centro de investigación o Institución: Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

más información sobre Molecular basis of immune deficiency in Wolf-Hirschhorn Syndrome (4p-)

Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming

2016

Senior Researcher : Antonio Baonza Cuenca Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Regeneration as a model to identify molecular mechanisms involved in cellular reprogramming

Study of the functional implications of GRK2 serine-threonine kinase in Hereditary Haemorrhagic Telangiectasia

2011

Senior Researcher : Petronila Penela Márquez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Study of the functional implications of GRK2 serine-threonine kinase in Hereditary Haemorrhagic Telangiectasia

Alternative therapies for inherited metabolic diseases

2008

Senior Researcher : Alejandra Gámez Abascal Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Alternative therapies for inherited metabolic diseases

Analysis using genetically modified mice of the possible role of alpha-synuclein in the pathogenesis of Huntington's disease

2008

Senior Researcher : José Javier Lucas Lozano Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Analysis using genetically modified mice of the possible role of alpha-synuclein in the pathogenesis of Huntington's disease

Transcription factors and heterochromatin formation in Drosophila

2008

Senior Researcher : Natalia Azpiazu Torres Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Transcription factors and heterochromatin formation in Drosophila

Synthetic nanoparticles as an innovative treatment for sepsis (SPRINT-4-SEPSIS)

2018

Senior Researcher : Antonio Artigas Raventós Research Centre or Institution : Instituto de Investigación e Innovación Parc Taulí (I3PT), Corporación Sanitaria i Universitaria Parc Taulí

more information on Synthetic nanoparticles as an innovative treatment for sepsis (SPRINT-4-SEPSIS)

Risk Assesment of Bacterial Sepsis using multiomic and bioinformatics tools: an approach towards the Precision Medicine in Infectious Diseases

2018

Senior Researcher : María Teresa Coque González

more information on Risk Assesment of Bacterial Sepsis using multiomic and bioinformatics tools: an approach towards the Precision Medicine in Infectious Diseases

Extracellular vesicles biomarkers for the diagnosis and prognosis of post-surgical septic shock

2018

Senior Researcher : Eduardo Tamayo Gómez Research Centre or Institution : Hospital Clínico Universitario de Valladolid

more information on Extracellular vesicles biomarkers for the diagnosis and prognosis of post-surgical septic shock

The function of the E3 ubiquitin ligase APC/C-Cdh1 in Fragile X Syndrome. Possible therapeutic application

2016

Senior Researcher : Ángeles Almeida Parra Research Centre or Institution : Instituto de Investigación Biomédica de Salamanca (IBSAL). CSIC-Universidad de Salamanca.

more information on The function of the E3 ubiquitin ligase APC/C-Cdh1 in Fragile X Syndrome. Possible therapeutic application

Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. Rescue of the phenotype and cell transplantation

2016

Senior Researcher : Carlos Vicario Abejón Research Centre or Institution : Instituto Cajal. CSIC. Madrid.

more information on Effect of mutations in the glucocerebrosidase-1 gene on iPS cell-derived neurons from Parkinson´s disease patients. Rescue of the phenotype and cell transplantation

Models for congenital muscular dystrophies: the search for phenotype suppressors

2014

Senior Researcher : Enrique Martín Blanco Research Centre or Institution : Instituto de Biología Molecular de Barcelona. CSIC.

more information on Models for congenital muscular dystrophies: the search for phenotype suppressors

Identification of the function of the Wt1gene in Huntington's disease

2014

Senior Researcher : Ofelia M. Martínez Estrada Research Centre or Institution : Departamento de Biología Celular. Universidad de Barcelona

more information on Identification of the function of the Wt1gene in Huntington's disease

Epigenetic study in vivo of the role of retinoic acid in the regeneration of ciliate cells

2011

Senior Researcher : Berta Alsina Español Research Centre or Institution : Universidad Pompeu Fabra-PRBB. Barcelona.

more information on Epigenetic study in vivo of the role of retinoic acid in the regeneration of ciliate cells

Cellular therapy for West's syndrome

2011

Senior Researcher : Manuel Álvarez Dolado Research Centre or Institution : CABIMER. CSIC

more information on Cellular therapy for West's syndrome

Chicken embryonic stem cells. Study of the differentiation between somatic and germinal lineages and between mesodermic and endodermic lineages

2011

Senior Researcher : Federica Bertocchini Bertocchini Research Centre or Institution : IBBTEC-Universidad de Cantabria-CSIC. Santander.

more information on Chicken embryonic stem cells. Study of the differentiation between somatic and germinal lineages and between mesodermic and endodermic lineages

Study of the neuroprotector capacity of the epithelial cells of the choroid plexi as a potential regenerative therapy for Alzheimer's disease

2011

Senior Researcher : Eva María Carro Díaz Research Centre or Institution : Instituto de Investigación Hospital 2 de Octubre. Madrid.

more information on Study of the neuroprotector capacity of the epithelial cells of the choroid plexi as a potential regenerative therapy for Alzheimer's disease

The generation of iPSC cells for the study of neurodevelopmental diseases: autism and William's syndrome

2011

Senior Researcher : Ivon Cuscó Martí Research Centre or Institution : Centros de Investigación Biomédica en Red (CIBER)-Universidad Pompeu Fabra. Barcelona

more information on The generation of iPSC cells for the study of neurodevelopmental diseases: autism and William's syndrome

Nanotechnologically reprogrammed cellular medicines

2011

Senior Researcher : Marcos García Fuentes Research Centre or Institution : Centro Singular en Medicina Molecular y Enfermedades Crónicas. Universidad de Santiago de Compostela

more information on Nanotechnologically reprogrammed cellular medicines

In vivo nuclear reprogramming and the functional interrelationship between p27 and SOX2

2011

Senior Researcher : Manuel Serrano Marugán Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid

more information on In vivo nuclear reprogramming and the functional interrelationship between p27 and SOX2

Myosin II integrates the mechanical signals of the cellular micro-environment and controls the migration and differentiation of stem cells

2011

Senior Researcher : Miguel Vicente Manzanares Research Centre or Institution : Universidad Autónoma de Madrid.

more information on Myosin II integrates the mechanical signals of the cellular micro-environment and controls the migration and differentiation of stem cells

The subarachnoid administration of previously cryopreserved allogenic stromal cells in traumatic spinal lesion

2011

Investigador Principal: Mercedes Zurita Castillo Centro de investigación o Institución: Hospital Universitario Puerta de Hierro Majadahonda. Madrid.

más información sobre The subarachnoid administration of previously cryopreserved allogenic stromal cells in traumatic spinal lesion

The complete sequencing of the exomic genome of systemic lupus erythematosus in families of European origin with multiple cases: the identification of rare mutations and their functional consequences

2011

Investigador Principal: Marta Eugenia Alarcón Riquelme Centro de investigación o Institución: Centro Pfizer. Universidad de Granada. Junta de Andalucía de Genómica e Investigación Oncológica (GENYO). Granada

más información sobre The complete sequencing of the exomic genome of systemic lupus erythematosus in families of European origin with multiple cases: the identification of rare mutations and their functional consequences

The identification of new genes responsible for Hereditary Dystrophies of the Retina using Next-Generation Sequencing technology and the determination of associated pathogenic mechanisms

2011

Senior Researcher : Guillermo Antiñolo Gil Research Centre or Institution : Hospital Universitario Virgen del Rocío. Sevilla.

more information on The identification of new genes responsible for Hereditary Dystrophies of the Retina using Next-Generation Sequencing technology and the determination of associated pathogenic mechanisms

Hereditary metabolic diseases: searching for new genes that cause diseases and research into new therapeutic strategies

2011

Senior Researcher : Mª del Pilar Rodríguez Pombo Research Centre or Institution : Universidad Autónoma de Madrid.

more information on Hereditary metabolic diseases: searching for new genes that cause diseases and research into new therapeutic strategies

Study of the methylome/genome relationship and their points in common in systemic autoimmune diseases: SLE, RA and SSc

2011

Senior Researcher : Esteban Ballestar Tarín Research Centre or Institution : Instituto de Investigación Biomédica de Bellvitge (IDIBELL). Barcelona.

more information on Study of the methylome/genome relationship and their points in common in systemic autoimmune diseases: SLE, RA and SSc

Nutri-epigenetics of the control of body adiposity: studies in animal models of differing susceptibility to obesity based on nutritional interventions in early stages in life

2011

Senior Researcher : María Luisa Bonet Piña Research Centre or Institution : Universidad de las Islas Baleares. Mallorca

more information on Nutri-epigenetics of the control of body adiposity: studies in animal models of differing susceptibility to obesity based on nutritional interventions in early stages in life

Epigenome and transcriptome of nociception (Functional epigenomics of nociception)

2011

Senior Researcher : Ángel Manuel Carrión Rodríguez Research Centre or Institution : Facultad de Ciencias Experimentales. Universidad Pablo de Olavide. Sevilla

more information on Epigenome and transcriptome of nociception (Functional epigenomics of nociception)

The acetylomes of neural differentiation

2011

Senior Researcher : Mario Fernández Fraga Research Centre or Institution : Instituto Universitario de Oncología del Principado de Asturias (IUOPA)-Universidad de Oviedo.

more information on The acetylomes of neural differentiation

Epigenetic alterations in tetraploid neurones and Alzheimer's disease

2011

Senior Researcher : José María Frade López Research Centre or Institution : Instituto Cajal. CSIC. Madrid.

more information on Epigenetic alterations in tetraploid neurones and Alzheimer's disease

Experimental study of the epigenetic implications of changes in the composition of fatty acids in the diet during pregnancy and their consequences for adult offspring

2011

Senior Researcher : Emilio Herrera Castillón Research Centre or Institution : Universidad San Pablo-CEU. Madrid.

more information on Experimental study of the epigenetic implications of changes in the composition of fatty acids in the diet during pregnancy and their consequences for adult offspring

The epigenetic regulation of reelin in Alzheimer's disease

2011

Senior Researcher : Javier Sáez Valero Research Centre or Institution : Instituto de Neurociencias. CSIC-Universidad Miguel Hernández. Alicante.

more information on The epigenetic regulation of reelin in Alzheimer's disease

Azotobacter vinelandii as bio-factories for producing hydrogen

2008

Senior Researcher : Juan Imperial Ródenas Research Centre or Institution : Centro de Biotecnología y Genómica de Plantas. Universidad Politécnica de Madrid

more information on Azotobacter vinelandii as bio-factories for producing hydrogen

Using genetic engineering to obtain strains of Clostridium cellulolyticum and Rhodobacter capsulatus that overproduce hydrogen

2008

Senior Researcher : Alberto Sola Landa Research Centre or Institution : Instituto de Biotecnología de León (INBIOTEC).

more information on Using genetic engineering to obtain strains of Clostridium cellulolyticum and Rhodobacter capsulatus that overproduce hydrogen

Testing xenoexpression as gene therapy for mitochondrial diseases

2008

Senior Researcher : Patricio Fernández Silva Research Centre or Institution : Facultad de Veterinaria. Universidad de Zaragoza

more information on Testing xenoexpression as gene therapy for mitochondrial diseases

Genetic and cellular basis of 16p11.2-p12.2 microdeletion syndrome and related neural disorders

2008

Senior Researcher : Marcos Malumbres Martínez Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid

more information on Genetic and cellular basis of 16p11.2-p12.2 microdeletion syndrome and related neural disorders

Role of epigenetic mechanisms in the processes of learning and memory

2008

Investigador Principal: Ángel Manuel Carrión Rodríguez Centro de investigación o Institución: Faculty of Experimental Sciences. Pablo de Olavide University. Sevilla

más información sobre Role of epigenetic mechanisms in the processes of learning and memory

Association between non-coding RNAs in ultra-conserved regions (T-UCR) and the epigenome: involvement in cancer

2008

Investigador Principal: Manel Esteller Badosa Centro de investigación o Institución: Epigenetics and Cancer Biology Program. Bellvitge Biomedical Research Institute (IDIBELL). Barcelona. (Spain)

más información sobre Association between non-coding RNAs in ultra-conserved regions (T-UCR) and the epigenome: involvement in cancer

Search and identification of new genetic and epigenetic causes of autistic spectrum disorders: design and implementation of a targeted high-resolution array with key elements of the epigenetic machinery

2008

Investigador Principal: María del Carmen Orellana Alonso Centro de investigación o Institución: Hospital Universitario La Fe. Valencia.

más información sobre Search and identification of new genetic and epigenetic causes of autistic spectrum disorders: design and implementation of a targeted high-resolution array with key elements of the epigenetic machinery

Epigenetic control of cell differentiation and pluripotency by BRAF35 AND iBRAF proteins

2008

Investigador Principal: José Carlos Reyes Rosa Centro de investigación o Institución: Centro Andaluz de Biología Molecular y Medicina Regenerativa (CSIC)

más información sobre Epigenetic control of cell differentiation and pluripotency by BRAF35 AND iBRAF proteins

Epigenetic regulation of the maintenance of genomic stability during mitotic and meiotic cell cycle

2008

Senior Researcher : Pedro Antonio San Segundo Nieto Research Centre or Institution : Instituto de Microbiología Bioquímica. CSIC-Universidad de Salamanca.

more information on Epigenetic regulation of the maintenance of genomic stability during mitotic and meiotic cell cycle

Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system

2008

Senior Researcher : Miguel Ángel Vidal Caballero Research Centre or Institution : Centro de Investigaciones Biológicas (CSIC)

more information on Epigenetic regulation mediated by Ring1A/Ring1B, the ubiquitin ligases of the Polycomb system

Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes

2008

Investigador Principal: Manuel Arruebo Gordo Centro de investigación o Institución: Institute of Nanoscience of Aragón. University of Zaragoza.

más información sobre Phototherapy: resonant gold nanoparticles in the near infrared for photothermal ablation of tumour cells and for activation of therapeutic genes

Application of genetic analyses for the creation of germplasm banks in teleostei

2008

Investigador Principal: Vanesa Robles Rodríguez Centro de investigación o Institución: Departamento de Biología Molecular e Instituto de Desarrollo Ganadero y Sanidad Animal (INDEGSAL). Universidad de León

más información sobre Application of genetic analyses for the creation of germplasm banks in teleostei

High resolution profiles of acetylation and methylation of histones in the epigenome of Arabidopsis thaliana: functional connection with the biological clock

2008

Investigador Principal: Paloma Más Martínez Centro de investigación o Institución: Consorcio CSIC-IRTA-UAB. Centro de Investigación en Agrigenómica (CRAG). Barcelona

más información sobre High resolution profiles of acetylation and methylation of histones in the epigenome of Arabidopsis thaliana: functional connection with the biological clock

H2 production from glycerol with the aid of microbial cells isolated from the extremophile ecosystem of Rio Tinto

2008

Senior Researcher : Víctor Manuel Fernández López Research Centre or Institution : Instituto de Catálisis y Petroleoquímica. CSIC. Madrid.

more information on H2 production from glycerol with the aid of microbial cells isolated from the extremophile ecosystem of Rio Tinto

Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype

2006

Senior Researcher : Carlos Pipaón González Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander.

more information on Study of the role of the epigenetic mechanisms in the Fanconi Anaemia cancer tendency phenotype

Study of the molecular foundations of congenital malformations: cardiovascular, oculofacial and skeletal

2006

Senior Researcher : María José Trujillo Tiebas Research Centre or Institution : Fundación Jiménez Díaz. Madrid

more information on Study of the molecular foundations of congenital malformations: cardiovascular, oculofacial and skeletal

Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations

2006

Senior Researcher : Francisco Barros Angueira Research Centre or Institution : Hospital Clínico Universitario de Santiago de Compostela. Fundación Pública Galega de Medicina Xenómica.

more information on Clinical application of pharmacogenetic markers in the treatment of colorectal cancer. Establishment of therapeutic guidelines and recommendations

Search for differential genetic markers between two different types of response to the same allergenic exposure: tolerance versus sensitisation

2006

Senior Researcher : Blanca Cárdaba Olombrada Research Centre or Institution : Fundación Jiménez Díaz. Madrid

more information on Search for differential genetic markers between two different types of response to the same allergenic exposure: tolerance versus sensitisation

Transportome as a predictive response element: the importance of nucleoside transporters

2006

Senior Researcher : Francisco Javier Casado Merediz Research Centre or Institution : Facultad de Biología. Universidad de Barcelona

more information on Transportome as a predictive response element: the importance of nucleoside transporters

Genomic research in patients with an initial schizophrenic episode: identification of genetic and pharmacogenetic markers

2006

Senior Researcher : Benedicto Crespo-Facorro Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander.

more information on Genomic research in patients with an initial schizophrenic episode: identification of genetic and pharmacogenetic markers

Clinical genetic studies of a cohort with hereditary Alzheimer's disease (new locus)

2006

Senior Researcher : Adriano Jiménez Escrig Research Centre or Institution : Fundación para la Investigación Biomédica. Hospital Universitario Ramón y Cajal. Madrid.

more information on Clinical genetic studies of a cohort with hereditary Alzheimer's disease (new locus)

Pharmacogenetics in colorectal cancer

2006

Senior Researcher : Luis Andrés López Fernández Research Centre or Institution : Fundación para la Investigación Biomédica del Hospital Gregorio Marañón. Madrid

more information on Pharmacogenetics in colorectal cancer

Geno-tPA: Search for predictive genetic patterns for the progress of patients with ischemic ictus following treatment with t-PA

2006

Senior Researcher : Joan Montaner Villalonga Research Centre or Institution : Fundació Institut Recerca Vall d´Hebron. Hospital Vall d´Hebron. Barcelona

more information on Geno-tPA: Search for predictive genetic patterns for the progress of patients with ischemic ictus following treatment with t-PA

Implications of mevalonic acid, Wnt and oestrogen pathways in osteoporosis and response to antiresorptive drugs

2006

Senior Researcher : José A. Riancho Moral Research Centre or Institution : Hospital Universitario Marqués de Valdecilla. Universidad de Cantabria. Santander.

more information on Implications of mevalonic acid, Wnt and oestrogen pathways in osteoporosis and response to antiresorptive drugs

Taxane pharmacogenetics: neurotoxicity and therapeutic efficacy

2006

Senior Researcher : Cristina Rodríguez González de Antona Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid

more information on Taxane pharmacogenetics: neurotoxicity and therapeutic efficacy

Study of the impact of genetic polymorphisms in the toxicity of the antiretroviral drugs used to treat HIV

2006

Senior Researcher : Sonia María Rodríguez Nóvoa Research Centre or Institution : Hospital Carlos III. Madrid.

more information on Study of the impact of genetic polymorphisms in the toxicity of the antiretroviral drugs used to treat HIV

Intestinal inflammatory diseases: susceptibility and pharmacogenetic markers

2006

Senior Researcher : María Elena Urcelay García Research Centre or Institution : Hospital Universitario Clínico San Carlos. Madrid.

more information on Intestinal inflammatory diseases: susceptibility and pharmacogenetic markers

Influence of genetic and pharmacological factors on innate immunity and immune response in the development of post-transplant arteriosclerosis

2006

Senior Researcher : José María Morales Cerdán Research Centre or Institution : Hospital Universitario 2 de Octubre. Madrid.

more information on Influence of genetic and pharmacological factors on innate immunity and immune response in the development of post-transplant arteriosclerosis

Novel immunotherapeutic strategies against T-ALL, a rare pediatric disease

2018

Senior Researcher : María Luisa Toribio García Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Novel immunotherapeutic strategies against T-ALL, a rare pediatric disease

Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine

2018

Senior Researcher : José Fernández Piqueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Integration of genomic and epigenomics strategies for the analysis of T lymphoblastic neoplasms in the context of a precision individualized medicine

Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis

2018

Senior Researcher : Héctor Peinado Selgas Research Centre or Institution : Centro Nacional de Investigaciones Oncológicas (CNIO). Madrid

more information on Developing a targeted therapy to promote melanoma immune-recognition and suppress metastasis

Interactome rewiring by phosphorylation and acetylation barcodes: implications in metabolic reprogramming in breast cancer

2018

Senior Researcher : Federico Mayor Menéndez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Interactome rewiring by phosphorylation and acetylation barcodes: implications in metabolic reprogramming in breast cancer

Comprehensive virus-host protein interactome by the use of yeast-two-hybrid coupled to next-generation sequencing analysis

2018

Senior Researcher : Margarita Salas Falgueras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Comprehensive virus-host protein interactome by the use of yeast-two-hybrid coupled to next-generation sequencing analysis

Production of second generation prebiotics and polyphenol glycosides. Validation of its bioactive properties for use in functional food

2018

Senior Researcher : María Fernández Lobato Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Production of second generation prebiotics and polyphenol glycosides. Validation of its bioactive properties for use in functional food

Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases

2016

Senior Researcher : Paola Bovolenta Nicolao Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Systemic analysis of the gene regulatory networks involved in the specification and maintenance of the retinal pigment epithelium: towards new therapies for retinal degenerative diseases

AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies

2016

Senior Researcher : Jorgina Satrústegui Gil-Delgado Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on AGC1 deficiency and calcium signaling in mitochondria: a new disease model for the study of pathogenic mechanisms and for the development of therapeutic strategies

Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia

2016

Senior Researcher : Hisse Martien van Santen Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Development and preclinical testing of simultaneous dual engagement chimeric antigen receptors (SiDECARs) against acute myeloid leukemia

Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons

2016

Senior Researcher : María Jesús Bullido Gómez-Heras Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Role of the lysosomal protein LAMP2 in the AD-like phenotype induced by HSV-1: Study of the LAMP2 interactome in virus infected neurons

Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators

2016

Senior Researcher : Yolanda Revilla Novella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Development of therapeutic compounds based on the molecular interaction sites between the A238L viral protein and the transcriptional complexes that regulate the synthesis of pro-inflammatory and tumor mediators

Using animal models for testing interventions targeting malnutrition and stunting in children

2016

Senior Researcher : Fernando Martín Belmonte Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Using animal models for testing interventions targeting malnutrition and stunting in children

Genome and transcriptome analysis to identify splicing defects and in vivo evaluation of antisense therapy

2014

Senior Researcher : Lourdes Ruiz Desviat Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Genome and transcriptome analysis to identify splicing defects and in vivo evaluation of antisense therapy

Molecular mechanisms in Dravet's syndrome

2014

Senior Researcher : Francisco Zafra Gómez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Molecular mechanisms in Dravet's syndrome

Exosome optimisation for therapeutic use. The role of tetraspan in-rich micro domains in the biogenesis and function of exosomes

2014

Senior Researcher : María Yáñez Mó Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Exosome optimisation for therapeutic use. The role of tetraspan in-rich micro domains in the biogenesis and function of exosomes

Study of the tissue-specific interactome of the GRK2 node involved in insulin resistance and obesity: pathological repercussions

2014

Senior Researcher : Cristina Murga Montesinos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Study of the tissue-specific interactome of the GRK2 node involved in insulin resistance and obesity: pathological repercussions

New functional complexes deriving from the interaction of Gaq with proteins that contain PB1 domains, and the possible repercussion of this in cardiovascular pathologies

2014

Senior Researcher : Catalina Ribas Núñez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on New functional complexes deriving from the interaction of Gaq with proteins that contain PB1 domains, and the possible repercussion of this in cardiovascular pathologies

The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase

2014

Senior Researcher : José Manuel Cuezva Marcos Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on The oncogenic function of IF1: the inhibitor of mitochondrial H+-ATP syntase

The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer

2014

Senior Researcher : César Jesús de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on The antitumor effect of GCN2 kinase: the relationship between nutritional stress, protein synthesis and skin cancer

Studies of tumorigenesis in Drosophila: possible clinical implications

2014

Senior Researcher : Ginés Morata Pérez Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Studies of tumorigenesis in Drosophila: possible clinical implications

The molecular bases for variability in the presentation and clinical development of Wilson's disease

2011

Senior Researcher : Ignacio Vicente-Sandoval Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on The molecular bases for variability in the presentation and clinical development of Wilson's disease

Molecular and cellular bases of mental retardation associated with "Fragile X" syndrome

2008

Senior Researcher : José Antonio Esteban García Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Molecular and cellular bases of mental retardation associated with "Fragile X" syndrome

Functional characterisation of the eIF2alpha, GCN2 and PERK kinases in the molecular memory mechanisms

2006

Senior Researcher : César de Haro Castella Research Centre or Institution : Centro de Biología Molecular "Severo Ochoa". CSIC-Universidad Autónoma de Madrid

more information on Functional characterisation of the eIF2alpha, GCN2 and PERK kinases in the molecular memory mechanisms

Research projects